Interannual to decadal variations in Earth global temperature estimates have often been identified with El Nino Southern Oscillation (ENSO) events. However, we show that variability on time scales of 2-15 years in mean annual global land surface temperature anomalies T-avg are more closely correlated with variability in sea surface temperatures...
The detection and determination of clusters has been of special interest among researchers from different fields for a long time. In particular, assessing whether the clusters are significant is a question that has been asked by a number of experimenters. In Fuentes and Casella (2009), the authors put forth a...
Response patterns are of importance to survey researchers because of the insight they provide into the thought processes respondents use to answer survey questions. In this paper we propose the use of structural equation modeling to examine response patterns and develop a permutation test to quantify the likelihood of observing...
RNA sequencing (RNA-Seq) is the current method of choice for characterizing transcriptomes and
quantifying gene expression changes. This next generation sequencing-based method provides unprecedented
depth and resolution. The negative binomial (NB) probability distribution has been shown to be a
useful model for frequencies of mapped RNA-Seq reads and consequently provides...
We present a generalized estimating equations approach for estimating the concordance correlation coefficient and the
kappa coefficient from sample survey data. The estimates and their accompanying standard error need to correctly account
for the sampling design. Weighted measures of the concordance correlation coefficient and the kappa coefficient, along with
the...
The rapid worldwide emergence of the amphibian pathogen Batrachochytrium dendrobatidis (Bd) is having a profound negative impact on biodiversity. However, global research efforts are fragmented and an overarching synthesis of global infection data is lacking. Here, we provide results from a community tool for the compilation of worldwide Bd presence...
Differential investment in offspring has been reported for many mammals, often in the context of the Trivers–
Willard model of male-biased investment, but evidence of differential investment in pronghorns (Antilocapra
americana) is largely lacking. We assessed the causes and consequences of different birth masses of littermate
fawns in a pronghorn...
When assessing differential gene expression from RNA sequencing data, commonly used statistical tests tend to have greater power to detect differential expression of genes encoding longer transcripts. This phenomenon, called "length bias", will influence subsequent analyses such as Gene Ontology enrichment analysis. In the presence of length bias, Gene Ontology...
The varying-coefficient model is flexible and powerful for modeling the dynamic changes of regression coefficients. It is important to identify significant covariates associated with response variables, especially for high-dimensional settings where the number of covariates can be larger than the sample size. We consider model selection in the high-dimensional setting...
The "coupon collection problem" refers to a class of occupancy problems,
in which j identical items are distributed, independently and at random,
to n cells, with no restrictions on multiple occupancy. Identifying the cells as
coupons, a coupon is "collected" if the cell is occupied by one or more of...