Mitotic recombination is a common autosomal mutation in mammalian cells involving crossover events between homologous chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous ...

Monocrotaline (MCT) is a member of a class of naturally occurring phytotoxins known as pyrrolizidine alkaloids (PAs). Exposure to PAs can result in liver and cardiopulmonary lesions as well as lymphoid organ atrophy. I ...

Lymphomas and leukemias are the most common cancer in children and young adults and in utero exposure to carcinogens may contribute to the etiology of these cancers. A polycyclic aromatic hydrocarbon (PAH), dibenzo[a,l ...

Exposure to TCDD suppresses the generation of immune responses through unknown mechanisms. Interestingly, TCDD enhances inflammatory responses to various stimuli. The goal of the studies presented in this thesis was to e ...

The Cottage Grove Reservoir has been impacted by a point source (Black Butte Mine), where mercury mining and processing has occurred within its watershed from the 1890's to the late 1960's. Total mercury concentrations ...

There is plenty of evidence from epidemiology studies supporting a link between certain components in the human diet and cancer incidence. It is estimated that 3-4 million annual cases of cancer could be prevented wor ...

Hydrocarbon solvents are widely used in the production of paints, adhesives, dyes, polymers, plastics, textiles, printing inks, agricultural products and pharmaceuticals. While the neuropathic potential of aliphatic so ...