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Browsing Department of Botany and Plant Pathology by Author "Fahlgren, Noah"

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Browsing Department of Botany and Plant Pathology by Author "Fahlgren, Noah"

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  • Fahlgren, Noah; Sullivan, Christopher M.; Kasschau, Krisitin D.; Chapman, Elisabeth J.; Cumbie, Jason S.; Montgomery, Taiowa A.; Gilbert, Sunny D.; Dasenko, Mark; Backman, Tyler W. H.; Givan, Scott A.; Carrington, James C. (Cold Spring Harbor Laboratory Press, 2009-05)
    The advent of high-throughput sequencing (HTS) methods has enabled direct approaches to quantitatively profile small RNA populations. However, these methods have been limited by several factors, including representation ...
  • Gu, Weifeng; Shirayama, Masaki; Conte Jr., Darryl; Vasale, Jessica; Batista, Pedro J.; Claycomb, Julie M.; Moresco, James J.; Youngman, Elaine; Keys, Jennifer; Stoltz, Matthew J.; Chen, Chun-Cheih G.; Chaves, Daniel A.; Duan, Shenghua E.; Kasschau, Krisitin D.; Fahlgren, Noah; Yates III, John R.; Mitani, Shohei; Carrington, James C.; Mello, Craig C. (Elsevier Inc., 2010-10-23)
    Endogenous small RNAs (endo-siRNAs) interact with Argonaute (AGO) proteins to mediate sequence-specific regulation of diverse biological processes. Here, we combine deep-sequencing and genetic approaches to explore the ...
  • Fischer, Sylvia E. J.; Montgomery, Taiowa A.; Zhang, Chi; Fahlgren, Noah; Breen, Peter C.; Hwang, Alexia; Sullivan, Christopher M.; Carrington, James C.; Ruvkun, Gary (Public Library of Science, 2011-11)
    Endogenous small interfering RNAs (siRNAs) are a class of naturally occuring regulatory RNAs found in fungi, plants, and animals. Some endogenous siRNAs are required to silence transposons or function in chromosome segre ...
  • Carbonell, Alberto; Fahlgren, Noah; Garcia-Ruiz, Hernan; Gilbert, Kerrigan B.; Montgomery, Taiowa A.; Nguyen, Tammy; Cuperus, Josh T.; Carrington, James C. (American Society of Plant Biologists, 2012-09)
    In RNA-directed silencing pathways, ternary complexes result from small RNA-guided ARGONAUTE (AGO) associating with target transcripts. Target transcripts are often silenced through direct cleavage (slicing), destabiliza ...
  • Kasschau, Kristin D.; Fahlgren, Noah; Chapman, Elisabeth J.; Sullivan, Christopher M.; Cumbie, Jason S.; Givan, Scott A.; Carrington, James C. (PLoS ONE, 2007-03)
    Eukaryotes contain a diversified set of small RNA-guided pathways that control genes, repeated sequences, and viruses at the transcriptional and posttranscriptional levels. Genome-wide profiles and analyses of small RNA ...
  • Klevebring, Daniel; Street, Nathaniel R.; Fahlgren, Noah; Kasschau, Krisitin D.; Carrington, James C.; Lundeberg, Joakim; Jansson, Stefan (BioMed Central, 2009-12-20)
    Background: Short RNAs, and in particular microRNAs, are important regulators of gene expression both within defined regulatory pathways and at the epigenetic scale. We investigated the short RNA (sRNA) population (18- ...
  • Fahlgren, Noah; Howell, Miya D.; Kasschau, Kristin D.; Sullivan, Christopher M.; Cumbie, Jason S.; Givan, Scott A.; Law, Theresa F.; Grant, Sarah R.; Dangl, Jeffrey L.; Carrington, James C. (PLoS ONE, 2007-02)
    In plants, microRNAs (miRNAs) comprise one of two classes of small RNAs that function primarily as negative regulators at the posttranscriptional level. Several MIRNA genes in the plant kingdom are ancient, with conserv ...
  • Cuperus, Josh T.; Montgomery, Taiowa A.; Fahlgren, Noah; Burke, Russell T.; Townsend, Tiffany; Sullivan, Christopher M.; Carrington, James C. (National Academy of Sciences, 2010-01-05)
    Transacting siRNA (tasiRNA) biogenesis in Arabidopsis is initiated by microRNA (miRNA) –guided cleavage of primary transcripts. In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)– miR390 complexes interact with ...
  • Fahlgren, Noah; Bollmann, Stephanie R.; Kasschau, Kristin D.; Cuperus, Josh T.; Press, Caroline M.; Sullivan, Christopher M.; Chapman, Elisabeth J.; Hoyer, J. Steen; Gilbert, Kerrigan B.; Grunwald, Niklaus J.; Carrington, James C. (Public Library of Science, 2013-10-21)
    In eukaryotes, RNA silencing pathways utilize 20-30-nucleotide small RNAs to regulate gene expression, specify and maintain chromatin structure, and repress viruses and mobile genetic elements. RNA silencing was likely p ...

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