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Department of Biochemistry and Biophysics

DSpace/Manakin Repository

Department of Biochemistry and Biophysics

Recent Submissions

  • Barbar, Elisar; Nyarko, Afua (Elsevier, 2015-01)
    Intrinsically disordered proteins (IDPs) are prevalent in macromolecular assemblies and are thought to mediate protein recognition in complex regulatory processes and signaling pathways. The formation of a polybivalent ...
  • Osborn, Andrew R.; Almabruk, Khaled H.; Holzwarth, Garrett; Asamizu, Shumpei; LaDu, Jane; Kean, Kelsey M.; Karplus, P. Andrew; Tanguay, Robert L.; Bakalinsky, Alan T.; Mahmud, Taifo (eLife Sciences Publications, 2015-05-12)
    Ultraviolet-protective compounds, such as mycosporine-like amino acids (MAAs) and related gadusols produced by some bacteria, fungi, algae, and marine invertebrates, are critical for the survival of reef-building corals ...
  • Zhang, Wei-Jian; Frei, Balz (Hindawi Publishing Corporation, 2015)
    In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in m ...
  • Perkins, Arden; Poole, Leslie B.; Karplus, P. Andrew (American Chemical Society, 2014-12-16)
    Peroxiredoxins (Prxs) make up an ancient family of enzymes that are the predominant peroxidases for nearly all organisms and play essential roles in reducing hydrogen peroxide, organic hydroperoxides, and peroxynitrite. ...
  • Driggers, Camden M.; Hartman, Steven J.; Karplus, P. Andrew (John Wiley & Sons, Inc., 2015-01)
    In some bacteria, cysteine is converted to cysteine sulfinic acid by cysteine dioxygenases (CDO) that are only ∼15–30% identical in sequence to mammalian CDOs. Among bacterial proteins having this range of sequence simil ...