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Browsing Department of Biochemistry and Biophysics by Author "Gombart, Adrian F."

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Browsing Department of Biochemistry and Biophysics by Author "Gombart, Adrian F."

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  • Kyme, Pierre; Thoennissen, Nils H.; Tseng, Ching Wen; Thoennissen, Gabriela B.; Wolf, Andrea J.; Shimada, Kenichi; Krug, Utz O.; Lee, Kunik; Muller-Tidow, Carsten; Berdel, Wolfgang E.; Hardy, W. David; Gombart, Adrian F.; Koeffler, H. Phillip; Liu, George Y. (American Society for Clinical Investigation, 2012-09)
    The myeloid-specific transcription factor, CCAAT/enhancer-binding protein epsilon (C/EBPε) is a critical mediator of myelopoiesis. Mutation of this gene is responsible for neutrophil-specific granule deficiency in humans ...
  • Guo, Chunxiao; Rosoha, Elena; Lowry, Malcolm B.; Borregaard, Niels; Gombart, Adrian F. (Elsevier, 2013-05)
    The vitamin D receptor (VDR) mediates the pleiotropic biologic effects of 1alpha,25 dihydroxy-vitamin D3. Recent in vitro studies suggested that curcumin and poly-unsaturated fatty acids (PUFAs) also bind to VDR with l ...
  • Okamoto, Ryoko; Gery, Sigal; Gombart, Adrian F.; Wang, Xuping; Castellani, Lawrence W.; Akagi, Tadayuki; Chen, Shuang; Arditi, Moshe; Ho, Quoc; Lusis, Aldons J.; Li, Quanlin; Koeffler, H. Phillip (Public Library of Science, 2014-01-28)
    The CCAAT/enhancer binding proteins (C/EBPs) are transcription factors involved in hematopoietic cell development and induction of several inflammatory mediators. C/EBPε is expressed only in myeloid cells including mono ...
  • Sun, Guihua; Li, Haitang; Wu, Xiwei; Covarrubias, Maricela; Scherer, Lisa; Meinking, Keith; Luk, Brian; Chomchan, Pritsana; Alluin, Jessica; Gombart, Adrian F.; Rossi, John J. (Oxford University Press, 2012-03)
    Using microRNA array analyses of in vitro HIV-1-infected CD4(+) cells, we find that several host microRNAs are significantly up- or downregulated around the time HIV-1 infection peaks in vitro. While microRNA-223 levels ...
  • Campbell, Yan; Fantacone, Mary L.; Gombart, Adrian F. (Springer, 2012-12)
    Background: Antimicrobial peptides (AMPs) are synthesized and secreted by immune and epithelial cells that are constantly exposed to environmental microbes. AMPs are essential for barrier defense and deficiencies lead to ...

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