Browsing Faculty Research Publications (Biochemistry and Biophysics) by Title

Now showing items 18-19 of 19

Short-Term Treatment With Rapamycin and Dietary Restriction Have Overlapping and Distinctive Effects in Young Mice

Fok, Wilson C.; Zhang, Yiqiang; Salmon, Adam B.; Bhattacharya, Arunabh; Gunda, Rakesh; Jones, Dean; Ward, Walter; Fisher, Kathleen; Richardson, Arlan; Perez, Viviana I. (Oxford University Press, 2013-02)

Because rapamycin, an inhibitor of the nutrient sensor mammalian target of rapamycin, and dietary restriction both increase life span of mice, it has been hypothesized that they act through similar mechanisms. To test th ...
Yeast POS5 NADH Kinase: Effects of a Mitochondrial Mutator Mutation on Mitochondrial Nucleotides

Wheeler, Linda J.; Mathews, Christopher K. (American Society for Biochemistry and Molecular Biology, 2012-09-07)

Saccharomyces cerevisiae contains three NAD⁺/NADH kinases, one of which is localized in mitochondria and phosphorylates NADH in preference to NAD⁺. Strand et al (Euk. Cell 2:809 (2003)) reported that a yeast mutation i ...