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Bioavailability of vitamin B-6 from test foods and metabolism of vitamin B-6 in men receiving supplementary pyridoxine

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dc.contributor.advisor Miller, Lorraine T.
dc.creator Wang, Kuen Wu
dc.date.accessioned 2012-01-26T19:50:57Z
dc.date.available 2012-01-26T19:50:57Z
dc.date.copyright 1982-12-08
dc.date.issued 1982-12-08
dc.identifier.uri http://hdl.handle.net/1957/27199
dc.description Graduation date: 1983 en_US
dc.description.abstract The bioavailability of vitamin B-6 from four selected foods was investigated in five men, aged 22 to 25 years, who were receiving a pyridoxine supplement. The subjects received a constant diet containing 1.34 mg of vitamin B-6 throughout this five-week study, except on Saturdays and Sundays when they ate their self-chosen diets. Starting on day 6 of week 1, following a five-day adjustment period, the subjects received orally 5-mg crystalline pyridoxine supplement daily, except on Tuesday and Thursday of each week. On these two days, the subjects were given orally 0 mg or 2 mg of crystalline pyridoxine, or test doses of bananas, filberts, soybeans and beef which contained around 2 mg of vitamin B-6. Vitamin B-6 was determined by microbiological assay with Saccharomyces uvarum. Vitamin B-6 bioavailability in the test food was determined by comparing 24-hour urinary total vitamin B-6 in response to the test food doses to that excreted following a 2-mg crystalline pyridoxine dose in each subject. Compared to the 100 percent bioavailability of the 2-mg crystalline PN dose, the average vitamin B-6 bioavailability in bananas was 115 + 32% and that in filberts, soybeans and beef was 93 + 8%, 73 + 20% and 87 + 7%, respectively. The metabolism of vitamin B-6 in pyridoxine-supplemented subjects was also investigated by measuring changes in plasma total vitamin B-6 which increased and was stablized after three weeks of pyridoxine supplementation. It was concluded that urinary total vitamin B-6 in pyridoxine-supplemented subjects can be used as a measure of vitamin B-6 bioavailability from test food doses. en_US
dc.language.iso en_US en_US
dc.subject.lcsh Vitamin B6 in human nutrition en_US
dc.title Bioavailability of vitamin B-6 from test foods and metabolism of vitamin B-6 in men receiving supplementary pyridoxine en_US
dc.type Thesis/Dissertation en_US
dc.degree.name Master of Science (M.S.) in Foods and Nutrition en_US
dc.degree.level Master's en_US
dc.degree.discipline Health and Human Sciences en_US
dc.degree.grantor Oregon State University en_US
dc.contributor.committeemember Gonzalez, Patricia
dc.contributor.committeemember Wang, Ann-Gau
dc.contributor.committeemember Barstow, Lynda
dc.contributor.committeemember Kabir, Hossein
dc.description.digitization File scanned at 300 ppi (Monochrome) using Scamax Scan+ V. on a Scanmax 412CD by InoTec in PDF format. LuraDocument PDF Compressor V. used for pdf compression and textual OCR. en_US
dc.description.peerreview no en_us

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