Graduate Thesis Or Dissertation
 

Elastic, plastic, and total strains in human and porcine pedicle trabecular bone and PU-foam after pedicle screw insertion by utilizing functional micro-CT imaging

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https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/z603r179z

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  • Pedicle screw breakage and loosening remain as clinical complications of short segment instrumentation procedures for spinal stabilization. This study has directly visualized and measured elastic, plastic and total vertebral pedicle trabecular bone full-field strains in the regions immediately surrounding the pedicle screw during pedicle screw insertion by utilizing functional microCT imaging and digital volume correlation. Human, porcine and polyurethane foam samples were analyzed and compared. Analysis showed that when osteoporotic human, normal human and porcine pedicle trabecular bone samples were compared, osteoporotic samples showed higher peak plastic strains and greater variability of these strains from their means. This suggests that osteoporotic human samples are non-uniformly elastic and plastic, while normal human and porcine samples are more uniformly elastic and plastic throughout the trabecular structure. PU-foams are not appropriate as models for pedicle trabecular bone in the in vivo environment since strain results showed dissimilar plastic and elastic strain magnitudes than human and porcine pedicle trabecular bone. This study may aid in the development of performance criteria for new PU-foams and improved pedicle screw designs.
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