Article

 

Infiltrative Myxoma of the Stifle Joint and Thigh in a Domestic Rabbit (Oryctolagus cuniculus) Public Deposited

https://ir.library.oregonstate.edu/concern/articles/7s75dd208

Descriptions

Attribute NameValues
Creator
Abstract
  • A 5-year-old, male, domestic rabbit had severe swelling of the left rear leg. Radiographs demonstrated a proliferative, infiltrative lesion involving the stifle joint, femur, and soft tissues of the thigh. Osteomyelitis or neoplasia was suspected, and the leg was surgically amputated. Grossly, a multilobular mass comprised cyst-like structures containing yellow mucinous material. Histologically, the mass formed coalescing lobules of stellate to rounded cells embedded in varying amounts of myxoid to collagenous matrix; some rimmed by narrow walls of metaplastic bone and/or cartilage; some infiltrated with plasma cells, lymphocytes, heterophils and histiocytes. On immunohistochemistry, neoplastic cells stained for vimentin but were negative for cytokeratin, sarcomeric actin, Mac387 and BLA.36. Cytokeratin was not detected in normal synovial cells. Radiographic, gross and histological findings are consistent with synovial myxoma seen in dogs and humans; however, because of extensive involvement of the limb in absence of confirmed metastatic disease, the term infiltrative synovial myxoma was applied.
  • Keywords: rabbit, pathology, myxoma, synovial
Resource Type
DOI
Date Available
Date Issued
Citation
  • Löhr, C. V., Hedge, Z. N., & Pool, R. R. (2012). Infiltrative myxoma of the stifle joint and thigh in a domestic rabbit (oryctolagus cuniculus). Journal of Comparative Pathology, 147(2-3), 218-222. doi: 10.1016/j.jcpa.2012.01.020
Journal Title
Journal Volume
  • 147
Journal Issue/Number
  • 43499
Academic Affiliation
Rights Statement
Publisher
Peer Reviewed
Language
Replaces

Relationships

Parents:

This work has no parents.

Items