Article
 

Analysis of koi herpesvirus latency in wild common carp and ornamental koi in Oregon, USA

Public Deposited

Downloadable Content

Download PDF
https://ir.library.oregonstate.edu/concern/articles/6m311q037

Descriptions

Attribute NameValues
Creator
Abstract
  • Koi herpesvirus (KHV) infection is associated with high mortalities in both common carp (Cyprinus carpio carpio) and koi carp (Cyprinus carpio koi) worldwide. Although acute infection has been reported in both domestic and wild common carp, the status of KHV latent infection is largely unknown in wild common carp. To investigate whether KHV latency is present in wild common carp, the distribution of KHV latent infection was investigated in two geographically distinct populations of wild common carp in Oregon, as well as in koi from an Oregon-based commercial supplier. Latent KHV infection was demonstrated in white blood cells from each of these populations. Although KHV isolated from acute infections has two distinct genetic groups, Asian and European, KHV detected in wild carp has not been genetically characterized. DNA sequences from ORF 25 to 26 that are unique between Asian and European were investigated in this study. KHV from captive koi and some wild common carp were found to have ORF-25-26 sequences similar to KHV-J (Asian), while the majority of KHV DNA detected in wild common carp has similarity to KHV-U/-I (European). In addition, DNA sequences from IL-10, and TNFR were sequenced and compared with no differences found, which suggests immune suppressor genes of KHV are conserved between KHV in wild common carp and koi, and is consistent with KHV-U, -I, -J. (C) 2012 Elsevier B.V. All rights reserved.
  • Keywords: Virus, Latency, KHV, Cyprinus carpio, Wild common carp, Disease, Variant
Resource Type
DOI
Date Available
Date Issued
Citation
  • Xu, J., Bently, J., Beck, L., Reed, A., Miller-Morgan, T., Heidel, J. R., . . . Jin, L. (2013). Analysis of koi herpesvirus latency in wild common carp and ornamental koi in oregon, USA. Journal of Virological Methods, 187(2), 372-379. doi: 10.1016/j.jviromet.2012.11.015
Journal Title
Journal Volume
  • 187
Journal Issue/Number
  • 2
Academic Affiliation
Rights Statement
Funding Statement (additional comments about funding)
  • This work was supported by American Koi Club Association, Nanjing Agricultural University and the Department of Biomedical Sciences, College of Veterinary Medicine at Oregon State University.
Publisher
Peer Reviewed
Language
Replaces

Relationships

Parents:

This work has no parents.

Items

Thumbnail Title Date Uploaded Visibility Actions
file details XuJia-RongVeterinaryMedicineAnalysisKoiHerpesvirus.pdf 2017-07-13 Public Download