Graduate Thesis Or Dissertation
 

X-ray study of an isobranched lecithin

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https://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/5m60qv93t

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  • Lipids, especially phospholipids, are very common but important molecules found in cells and animal tissue, performing many biological functions, particularly in membranes. Lipids, when mixed with water, spontaneously form ordered systems, such as micelles, vesicles and multibilayers. The size of these systems and their degree of ordering depend on the temperature and water content of the sample. One member of this most important class of molecules is 14-di-isoacyl-phosphatidyl-choline (14 iPC), a modified lipid. The goal of this study was to determine, via X-ray diffraction, the thermotropic phase behavior of bilayers formed by 14 iPC in excess water. In addition, the projected electron charge density perpendicular to the plane of the bilayer was deduced from Fourier transforms of the low-angle X-ray diffraction patterns. An investigation of the stacking disorder of bilayers was conducted by proposing models and comparing their predicted X-ray diffraction patterns with the observed data.
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  • File scanned at 300 ppi (Monochrome) using Capture Perfect 3.0.82 on a Canon DR-9080C in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR.
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