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Phytochemical, antioxidant and antibacterial potential of Elaeagnus kologa (Schlecht.) leaf

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  • Objective: To screen different solvent extracts of Elaeagnus kologa (E. kologa) leaf to determine the phytochemicals, potent antioxidant and antibacterial activity to find out the possible source of applied pharmaceutical formulations. Methods: Solvent extracts of leaf material were prepared using the Soxhlet apparatus. A study was performed on antioxidant activity of methanolic extract of leaf by 1-1-diphenyl-2-pierylhydrazyl method. The phenolic and flavonoid content of all the fractions were determined using high performance liquid chromatography. Leaves were also subjected to protein and carbohydrate test. Results: The total phenols, flavonoids were found to be high in petroleum ether as compare to other solvent fraction. The IC₅₀ value of methanolie extract of the sample was 62.20 μg/mL which showed significant antibacterial activity against Bacillus subtilis (Gram-positive). Conclusions: The present study suggests that the methanolic extract of E. kologa leaf possesses antioxidant and antibacterial properties. Such properties may be of great use in mitigating the detrimental effects of oxidative stress and reducing susceptibility to bacterial infection. Notably, extracts of E. kologa leaf also contain proteins and carbohydrates which add to its nutritional value.
  • Keywords: Psendomonas aeniginosa, Antibacterial, Bacillus subtilis, 1-1-Diphenyl-2-picrylhydrazyl, Medicinal plant, Antioxidant
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  • Merculieff, Z., Ramnath, S., Sankoli, S. M., Venkataramegowda, S., Murthy, G. S., & Ceballos, R. M. (2014). Phytochemical, antioxidant and antibacterial potential of Elaeagnus kologa (Schlecht.) leaf. Asian Pacific journal of tropical medicine, 7, S599-S602. doi:10.1016/S1995-7645(14)60295-9
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  • 7
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  • Supp. 1
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  • The authors are thankful to the US National Science Foundation REU Programme (Award # 1157152 and the US-India Education Foundation, Obama-Singh 214 Century Knowledge Initiative-USIEF/OSI/2012-2014) for financial assistance for this project.
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