Honors College Thesis

 

Test for Transgenerational Immune Priming in the Snail, Biomphalaria glabrata Public Deposited

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  • Transgenerational immune priming occurs when an adult is exposed to a parasite or other pathogen and then transmits information to its offspring through protective phenotypes to cope with the same pathogen (Moret, 2006). There has been evidence for transgenerational immune priming in various invertebrates (Tidbury et al. 2011). Here we tested for the presence of transgenerational immune priming in the Biomphalaria glabrata snails when challenged by exposure to the Schistosoma mansoni parasite. The experimental parent generation was challenged with a parasitic environment, while the control parent generation was not. The results were then determined based on the resistance or susceptibility of the F1 offspring generation. We found that parental challenge did not enhance offspring immunity through transgenerational immune priming. Key Words: Transgenerational immune priming, Schistosomiasis, Biomphalaria glabrata, Schistosoma mansoni
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