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Filtering by: Creator Adamson, Christopher Academic Affiliation Biochemistry and Biophysics

SLC23A1, the gene encoding sodium-dependent vitamin C transport protein 1 (SVCT1) : regulation of transcription and its functional consequences

Creator:

Michels, Alexander Johannes

Abstract:

Vitamin C is an essential component of the human diet. Uptake of vitamin C in the cell is regulated by the function of sodium-dependent vitamin C transporters (SVCTs). SVCT1 (encoded by the SLC23A1 gene) is expressed in the colon, liver and kidney, where it plays a vital role in determining...

Resource Type:

Dissertation
Hexachlorophene : its absorption, distribution, excretion, and biotransformation in the rat and rabbit and in vitro interaction with rat liver microsomes

Creator:

Gandolfi, Allen Jay

Abstract:

The fate of hexachlorophene, a widely used bactericide, was investigated using both intact male rats and rabbits and liver microsomes from male rats. Hexachlorophene administered intraperitoneally was found to be rapidly absorbed and distributed to all the tissues of the animals. Excretion of the chemical in both species occurred slowly,...

Resource Type:

Dissertation

Full Text:

wife, Judith, and my sons, Christopher and Matthew, for their cheerful support throughout the