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Filtering by: Committee Member Cebra, Christopher K. Academic Affiliation Biochemistry and Biophysics

DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

Creator:

Hooven, Louisa Ada

Abstract:

Exposure to polycyclic aromatic hydrocarbons such as benzo[a]pyrene (B[a]P) has been determined to be a risk factor for various forms of human cancer. PAH DNA adducts have been shown to cause mutations, but carcinogenesis is also accompanied by alterations in gene expression. Inhibiting individual cytochrome P450s could clarify the interaction...

Resource Type:

Dissertation

Full Text:

unwavering support. My appreciation is also extended to Dr. P. Shing Ho, Dr. Christopher K. Mathews, and Dr
Site-directed mutagenesis of the m2 muscarinic acetylcholine receptor

Creator:

Vogel, Walter Kevin

Resource Type:

Dissertation

Full Text:

thank Christopher K. Mathews, George J. Mpitsos, Thomas F. Murray, and Kensal E. van Holde for serving
Biochemical, molecular and physiological characterization of 1-butanol dehydrogenases of Pseudomonas butanovora in butane and 1-butanol metabolism

Creator:

Vangnai, Alisa S.

Abstract:

Butane-grown Pseudomonas butanovora oxidized butane by a soluble butane monooxygenase through the terminal pathway yielding 1 -butanol as the predominant product. Alcohol dehydrogenases (ADHs) involved in butane oxidation in P. butanovora were purified and characterized at the biochemical, genetic and physiological levels. Butane-grown P. butanovora expressed a type I soluble...

Resource Type:

Dissertation

Full Text:

. I would like to express my appreciation to my committee members: Dr. Christopher K. Mathews, Dr