Index Catalog // ScholarsArchive@OSU

Progress Towards the Total Synthesis of Bazzanin K

Creator:: Salvo, Patrick
Abstract:: Molecular chirality plays a critical role in chemistry, biology, and medicine. To study and better understand conformational chirality, it is necessary to obtain structurally interesting molecules that exhibit this form of chirality. Our lab utilizes total synthesis and methodological development to obtain conformationally chiral natural products of interest. We believe...
Resource Type:: Masters Thesis
Full Text:: Salvo, Author ACKNOWLEDGEMENTS I would sincerely like to thank my advisor Chris Beaudry

Racemic and Enantioselective Synthesis of Cavicularin

Creator:: Zhao, Peng
Abstract:: This dissertation describes the racemic and enantioselective synthesis cavicularin. Cavicularin is a macrocyclic bisbibenzyls family member natural product. It has been an attractive synthetic target due to its intriguing structure: the macrocyclic core imparts sufficient strain on the system to force one benzene rings to adopt a boat-shaped conformation, out...
Resource Type:: Dissertation
Full Text:: Zhao, Author ACKNOWLEDGEMENTS I would like to say special thanks to Professor Chris Beaudry. If

Computational Investigation into the Mechanisms and Origins of Selectivity in Selected Organic and Organometallic Chemical Processes

Creator:: Harper, Jordan L.
Abstract:: Put generally, the work I have conducted in my time at Oregon State University has been to answer two questions. The first of these is “Why do I get this particular product from this particular chemical reaction?” and the second is “How do the reagents in this chemical reaction lead...
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE DISSERTATION OF Jordan Luke Harper for the degree of Doctor of Philosophy in Chemistry

A Pyrone Diels–Alder Approach to Substituted Indoles and Carbazoles and the Synthesis of New Ropinirole Analogues

Creator:: Points, Gary L., III
Abstract:: Aromatic heterocycles are core structural motifs in natural products, pharmaceuticals and biological polymers. Indoles, in particular, represent a significant subclass of aromatic heterocycles, both in terms of sheer numbers, but also in biological and pharmaceutical relevance. As such, new methodologies for the synthesis of indoles represent an important and continually...
Resource Type:: Dissertation
Full Text:: Harper, Taisiya Feoktistova, Eliseo Quiroz, Bethany Parker, and Chris Bahro. To the generation of

Secondary metabolism in Streptomyces murayamaensis

Creator:: Melville, Chris R.
Resource Type:: Dissertation
Full Text:: ABSTRACT OF THE DISSERTATION OF Chris R. Melville for the degree of Doctor of Philosophy in Chemistry

Determination of Reaction Product Cross Sections in the ¹³⁶Xe + ²⁰⁸Pb Multi-nucleon Transfer Reaction at E[subscript cm] = 450 MeV

Creator:: Barrett, J. Spencer
Abstract:: The yields of 235 projectile-like and target-like fragments from the interaction of ¹³⁶Xe with a thick target of ²⁰⁸Pb at a center-of-mass energy, E[subscript cm], of 450 MeV were measured using γ-γ-γ coincidence data from Gammasphere and off-line γ-ray spectroscopy. The results give an expansive picture of the production cross...
Resource Type:: Dissertation
Full Text:: McCutchan and Alejandro Sonzagni. Thanks also goes out to Chris Chiara, Jessica Harker, and William

Stereospecific Synthesis of Stereotriad Motifs and Alkenes Using Enantioenriched sp³-Hybridized Carbenoids

Creator:: Xun, Sun
Abstract:: Enantioenriched sp³-hybridized carbenoid reagents CR1R2MX (X = nucleofuge, M = electrofuge) of different types were investigated for the synthesis of polysubstituted alkyl chains by iterative stereospecific reagent-controlled homologation (StReCH) and for the stereospecific connective synthesis of alkenes by eliminative cross-coupling. In the first part, putative enantioenriched α-chloroalkyllithiums (CHRLiCl) were employed...
Resource Type:: Dissertation
Full Text:: is translated into any desired configuration of the targeted alkene [(E)- or (Z)- isomer] as

Gene Expression, Structure Elucidation, and Bioactivity of Aspergillus Natural Products

Creator:: Neuhaus, George F.
Abstract:: The study of natural products (NPs) and their application has shaped humanity. Starting with the idea of using plants as medicine, it has now grown into the science of purifying and identifying organic molecules from nature to study their inherent biological activities. Understanding the molecular structures of NPs is the...
Resource Type:: Dissertation
Full Text:: secondary metabolite gene clusters were generated by Dr. Ming-Yueh Wu, Dr. Matthew E. Mead and Dr. Antonis

Total Synthesis of Aspidosperma Alkaloids Leuconoxine, Melodinine E and Mersicarpine and Synthetic Studies directed toward the Iboga Alkaloid Ibogaine: Progress directed toward the dimeric Cephalotaxus Alkaloid Cephalancetine C

Creator:: Kim, GilSoo
Abstract:: The first part of this manuscript is about the total synthesis of the aspidosperma alkaloids leuconoxine, melodinine E and mersicarpine. Our synthetic strategy used a radical translocation-conjugate addition cascade to construct the core of the natural product. Specifically, a vinyl radical was generated from the homolysis of the C–I bond...
Resource Type:: Dissertation
Full Text:: , Melodinine E and Mersicarpine and Synthetic Studies directed toward the Iboga Alkaloid Ibogaine: Progress

Synthetic studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit of rapamycin

Creator:: Jeffrey, Scott C.
Resource Type:: Dissertation
Full Text:: , and Chris Biermann First Baptist Church The Kinneys, The Durrells, The Sarpolas, The Amolds, The

ScholarsArchive@OSU

Progress Towards the Total Synthesis of Bazzanin K

Racemic and Enantioselective Synthesis of Cavicularin

Computational Investigation into the Mechanisms and Origins of Selectivity in Selected Organic and Organometallic Chemical Processes

A Pyrone Diels–Alder Approach to Substituted Indoles and Carbazoles and the Synthesis of New Ropinirole Analogues

Secondary metabolism in Streptomyces murayamaensis

Determination of Reaction Product Cross Sections in the ¹³⁶Xe + ²⁰⁸Pb Multi-nucleon Transfer Reaction at E[subscript cm] = 450 MeV

Stereospecific Synthesis of Stereotriad Motifs and Alkenes Using Enantioenriched sp³-Hybridized Carbenoids

Gene Expression, Structure Elucidation, and Bioactivity of Aspergillus Natural Products

Total Synthesis of Aspidosperma Alkaloids Leuconoxine, Melodinine E and Mersicarpine and Synthetic Studies directed toward the Iboga Alkaloid Ibogaine: Progress directed toward the dimeric Cephalotaxus Alkaloid Cephalancetine C

Synthetic studies n bioactive natural products. Part I, An approach towards the nootrophic agent huperzine A. Part II, Synthesis of the tricarbonyl subunit of rapamycin

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