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Filtering by: Creator Redle, Michael T. Remove constraint Creator: Redle, Michael T. Academic Affiliation Chemistry Remove constraint Academic Affiliation: Chemistry

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  • Himeradine A : synthetic efforts towards himeradine A and related natural products, a Michael reaction focused approach

    Creator:
    Collett, Nathan D.
    Abstract:
    Lycopodium alkaloids have generated enormous amounts of interest from the scientific community, both as synthetic targets and for their medicinal properties. Herein is described work towards a unifying approach to large segments of the Lycopodium family. An organocatalyzed intramolecular heteroatom Michael reaction method, for the construction of piperidine and piperizine...
    Resource Type:
    Dissertation
    Full Text:
    Related Natural Products, a Michael Reaction Focused Approach. AN ABSTRACT OF THE DISSERTATION OF

  • Development of organocatalyzed, intramolecular heteroatom Michael addition and application towards alkaloid synthesis

    Creator:
    Carlson, Erik
    Abstract:
    Effective methods for the enantiopure formation of substituted piperidine rings are significantly important due to their presence in alkaloid products. A valuable method to form these ring systems would be via an intramolecular heteroatom Michael addition from the corresponding enone or enal. Described herein is a methodolgy that has been...
    Resource Type:
    Masters Thesis
    Full Text:
    Organocatalyzed, Intramolecular Heteroatom Michael Addition and Application Towards Alkaloid Synthesis

  • Hydrogen abstraction from substituted t-butylbenzenes

    Creator:
    Harvey, Robert Louis
    Abstract:
    A study of the relative rates of the alkyl hydrogen abstraction from a series of meta and para substituted t-butylbenzenes by the chlorine atom at 70°C has been carried out. Application of the Hammett equation yielded a ρ value of -0.44 for the para compounds. Possible explanations for the non-linearity...
    Resource Type:
    Masters Thesis
    Full Text:
    Hydrogen abstraction from substituted t-butylbenzenes AN

  • Advanced studies on the biosynthesis of the streptolidine moiety of streptothricin F

    Creator:
    Jackson, Michael D.
    Resource Type:
    Dissertation
    Full Text:
    Moiety of Streptothricin F AN ABSTRACT OF THE THESIS OF Michael D. Jackson for the degree of Doctor of

  • Detection techniques for biomolecules using semi-conductor nanocrystals and magnetic beads as labels

    Creator:
    Chatterjee, Esha
    Abstract:
    Continued interest in the development of miniaturized and portable analytical platforms necessitates the exploration of sensitive methods for the detection of trace analytes. Nanomaterials, on account of their unique physical and chemical properties, are not only able to overcome many limitations of traditional detection reagents but also enable the exploration...
    Resource Type:
    Dissertation
    Full Text:
    Nanocrystals and Magnetic Beads as Labels Abstract approved: Vincent T. Remcho Continued

  • Synthesis of Intercalation Compounds and Nanocomposites of Inorganic Layered Hosts

    Creator:
    Liyanage, Medagama Liyanage Amila Udayanga
    Abstract:
    Novel synthetic strategies are developed to prepare new intercalation compounds and nanocomposites with several layered hosts (NiPS₃, Na-montmorillonite, MoS₂ and MoO₃). In these products, alkali metals are ionic intercalates and linear polymers, dendrimers or amines act as co-intercalates. In addition to new synthetic approaches, new structures are identified and characterized....
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________________________ Michael M. Lerner Novel synthetic strategies are developed to prepare new

  • Polylcaprolactone-Based Microfluidic Devices : Fabrication Methods and Applications in Low-Cost Analytical Devices

    Creator:
    Heist, Christopher A.
    Abstract:
    The overall concept of reducing laboratory operations to a scale that fits on a single microfluidic chip has been an attractive area of research over the last several decades. Despite a surge in research, few commercial success stories have been written. Lab-on-a-chip technologies have the capability to be cost effective...
    Resource Type:
    Dissertation
    Full Text:
    : ______________________________________________________ Vincent T. Remcho The overall concept of reducing laboratory operations to a scale that

  • A photoactivable microfluidic device for heavy metal ion extraction

    Creator:
    Nammoonnoy, Jintana
    Abstract:
    The development of microfluidic devices for heavy metal extraction is presented in this dissertation. Various research areas, covering subjects from photochromic compound syntheses to microchip fabrication techniques are explored to develop microfluidic devices capable of extracting heavy metal ions from drinking water. Through integration of the beneficial characteristics of both...
    Resource Type:
    Dissertation
    Full Text:
    : __________________________________________________________________ Vincent T. Remcho The development of microfluidic devices for heavy metal extraction is

  • Magnetic particles for selective extraction of trace analytes in microfluidic devices

    Creator:
    Tennico, Yolanda H.
    Abstract:
    The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
    Resource Type:
    Dissertation
    Full Text:
    Analytes in Microfluidic Devices Abstract approved: Vincent T. Remcho The development of

  • Monolithic sorbents for microscale separations

    Creator:
    Doneanu, Angela
    Abstract:
    Over the last decade, the miniaturization of analytical systems has become an increasingly important and interesting research area. Miniaturized systems offer many advantages, including reduced reagent and sample consumption, shorter analysis times, portability and disposability. This dissertation describes novel approaches in this direction, focusing on two areas: the miniaturization of...
    Resource Type:
    Dissertation
    Full Text:
    Ingle, Dr. Michael Lerner, Dr. Claudia Maier and Dr. Gregory Rorrer for offering the academic guidance