Index Catalog // ScholarsArchive@OSU

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Creator:: Wu, Yuanyuan
Abstract:: There has been a tremendous growth in interest in carbon nanodots (C-dots) in the past several years. As a nascent nanomaterial, C-dots have shown great promise in applications that benefit from their superior water dispersibility, low toxicity, non-blinking fluorescent output, chemical and biological compatibility, ease of functionalization and resistance to...
Resource Type:: Dissertation
Full Text:: Yuanyuan Wu for the degree of Doctor of Philosophy in Chemistry presented on March 7, 2016. Title

Synthesis of novel ambifunctional atropisomeric 2,2',6,6'-tetrasubstituted biphenyls and investigation of their properties and organocatalytic activity

Creator:: Sephton, Mark Alan
Abstract:: Ambifunctional axially chiral 2,2',6,6'-tetrasubstituted biphenyls containing nucleophilic (or basic) functional groups juxtaposed with hydrogen-bond donors were synthesized and their properties studied. Applications for the prepared biaryls as potential organocatalysts for enantioselective carbon-carbon bond forming reactions were examined. Processes investigated included: aldol, Michael, nitroaldol (Henry), and Baylis-Hillman reactions. The novel amidoamine...
Resource Type:: Dissertation
Full Text:: examined. Processes investigated included: aldol, Michael, nitroaldol (Henry), and Baylis-Hillman

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Creator:: Shaw, Subrata
Abstract:: This thesis describes the development of a new enantioselective synthetic method employing chiral cis-2,5-diaminobicyclo[2.2.2]octane-based organometallic catalysts. The significance of this new method to organic synthesis is illustrated with preparation of enantioenriched products that are transformed to important pharmaceutical agents. Chapter 1 provides a brief historical overview of asymmetric catalysis, especially...
Resource Type:: Dissertation
Full Text:: enantioselective Henry reaction of aldehydes with nitromethane, affording I3-nitro alcohols in high enantiomeric

Scaffold reactivity and large scale Synthesis of organocatalyzed Yamada-Otani Condensation product and investigation of the synthesis and properties of axially chiral 8,8'-biquinolyls and 8-(naphtha-1-yl)quinolines

Creator:: Banerjee, Somdev
Abstract:: In Part I, (4S,5R)-4,5-dimethyl-4-phenylcyclohex-2-enone (19a) was prepared in 73% yield with high enantio- and diastereo-selectivity (er > 98:2, dr > 20:1) on a multigram scale by a Yamada-Otani condensation between (E)-pent-3-en-2-one and 2-phenylpropanal catalyzed by a sulfonimide derivative of (S)-proline (18, HuaCat®). Synthetically useful transformations of the cyclohexenone product 19a...
Resource Type:: Dissertation
Full Text:: processes. Neither form of the compound was an effective catalyst for the Henry reaction between

The synthesis of a new amino alcohol derived from quinazoline

Creator:: Isensee, Robert William
Resource Type:: Dissertation
Full Text:: -quinzo1ineoarboxy1ie 'wii wu pre- pared. rori 2-arnino-1sophthflio oid. by renetion with forrnamld.e. Application

Centrifugal Partition Chromatography, Microfabrication, and a Smartphone-based Detection Platform : Analytical Chemistry from Preparative-scale Separation to Micro-scale Analysis

Creator:: Boonloed, Anukul
Abstract:: Analytical chemistry is an area of chemistry primarily focused on the study and use of instruments for separation, identification, and quantification of an analyte of interest. Specifically, separation science within analytical chemistry often refers to the process of dividing mixtures into their small component parts based on differences in their...
Resource Type:: Dissertation
Full Text:: support: Sumate Pengpumkiat, Dr. Yuanyuan Wu, Kelly Ramzy, Wei Xu, Peng Yu, Derek Wong, Saichon

Intercalation, exfoliation, and nanocomposites of layered inorganic compounds

Creator:: Sukpirom, Nipaka
Abstract:: The melt intercalation of poly(ethylene oxide) (PEO) between layers of MoO₃ and MPS3 (M=Mn,Cd) is obtained by heating the ground mixture and LiₓMoO₃, KₓMn₁-ₓ/₂PS₃, or KCd₁-ₓ/₂PS₃. The products are characterized by powder X-ray diffraction (XRD). Below the melting temperature of PEO (66 °C), intercalation rates and yields are low. By...
Resource Type:: Dissertation
Full Text:: . Sherry Zhang, R.avi Krishnamurthy, Henry Li, Wei Yan, Dr. Hiroyuki Enomoto (visiting professor), and Dr

Magnetic particles for selective extraction of trace analytes in microfluidic devices

Creator:: Tennico, Yolanda H.
Abstract:: The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Resource Type:: Dissertation

Fusion of Sn-124,Sn-132 with Ca-40,Ca-48

Creator:: Kolata, J. J., Roberts, A., Howard, A. M., Shapira, D., Liang, J. F., Gross, C. J., Varner, R. L., Kohley, Z., Villano, A. N., Amro, H., Loveland, W., and Chavez, E.
Abstract:: Fusion excitation functions for the reactions of Sn-¹²⁴,Sn-¹³² with Ca-⁴⁰,Ca-⁴⁸ were measured at energies near and below the Coulomb barrier. Weak sub-barrier fusion enhancement accounted for by coupling to the first 2(+) and 3(-) states in the target and projectile was observed for Sn-¹²⁴,Sn-¹³² + Ca-⁴⁸. However, the Sn-¹²⁴,Sn-¹³² +...
Resource Type:: Article
Full Text:: , MN 55455. §Present address: Henry Ford Health Systems, Henry Ford Hospital, Detroit, MI 48202

Comprehensive, Low-Cost Wicking Microfluidic Analytical Devices for Clinical Diagnostics and Environmental Analysis

Creator:: Bandara, Gayan C.
Abstract:: Analytical techniques are utilized in a wide variety of applications. Traditionally, analytical measurements are achieved by trained personnel in a laboratory setting using expensive scientific instruments, which limits their applicability in resource-limited areas and point-of-care applications. Therefore, the concept of enabling these laboratory-based qualitative and quantitative assays in microfluidic device...
Resource Type:: Dissertation
Full Text:: goes to Dr. Myra Koesdjojo, Dr. Genevieve Weber, Dr. Christopher Heist, Dr. Yuanyuan Wu, Dr. Sumate

ScholarsArchive@OSU

Carbon Nanodots as Biolabels for Fluorescence Immunoassays

Synthesis of novel ambifunctional atropisomeric 2,2',6,6'-tetrasubstituted biphenyls and investigation of their properties and organocatalytic activity

Cis-2,5-diaminobicyclo[2.2.2]octane : a novel C₂-symmetric scaffold for asymmetric catalysis

Scaffold reactivity and large scale Synthesis of organocatalyzed Yamada-Otani Condensation product and investigation of the synthesis and properties of axially chiral 8,8'-biquinolyls and 8-(naphtha-1-yl)quinolines

The synthesis of a new amino alcohol derived from quinazoline

Centrifugal Partition Chromatography, Microfabrication, and a Smartphone-based Detection Platform : Analytical Chemistry from Preparative-scale Separation to Micro-scale Analysis

Intercalation, exfoliation, and nanocomposites of layered inorganic compounds

Magnetic particles for selective extraction of trace analytes in microfluidic devices

Fusion of Sn-124,Sn-132 with Ca-40,Ca-48

Comprehensive, Low-Cost Wicking Microfluidic Analytical Devices for Clinical Diagnostics and Environmental Analysis

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