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Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: channel blocking activity (EC = 0.3 and 0.9 pg/mi, respectively). Stypoaldehyde, as well as the previously

Creator:: Phaosiri, Chanokporn
Abstract:: The discovery of the methylerythritol phosphate pathway (the MEP pathway) as an alternate pathway for isoprenoid biosynthesis in some organisms including most bacteria, malarial parasites and plants, but not in animals, has stimulated extensive studies in this area. Research has revealed the potential of finding novel antibacterials, antimalarial drugs, and...
Resource Type:: Dissertation
Full Text:: - diphosphate decarboxylase; vii, IPP isomerase. 7 A NADPH-dependent HMG-CoA reductase (EC 1.1.1.34

Creator:: Wang, Zhixing
Abstract:: Skin is the largest organ in the body that protects the organism from environmental, chemical and physical traumas of each passing day. The protective skin epidermal permeability barrier (EPB) is formed within the exterior layers of the epidermis, which are regularly sloughed off and repopulated by movement of inner cells....
Resource Type:: Dissertation
Full Text:: counterstained with DAPI (in blue). Images were taken at 40X magnification. EC: ectoderm, M: mesoderm, E

Creator:: Andrianasolo, Eric Hajaniriana
Abstract:: This thesis is an investigation of the natural products deriving from marine algae and cyanobacteria and has resulted in the discovery of eleven new secondary metabolites. The structure elucidations of these new molecules were performed using a variety of spectroscopic techniques. Four new macrolides were isolated and characterized from the...
Resource Type:: Dissertation
Full Text:: Dimethylsulfoxide DNMT-1 DNA Methyltransferase 1 EC Effective Concentration EDTA Ethylenediaminetetraacetic

ScholarsArchive@OSU