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Filtering by: Committee Member Maier, Claudia Academic Affiliation College of Pharmacy

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:

Han, Bingnan

Abstract:

This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...

Resource Type:

Dissertation

Full Text:

. George Constantine, Dr. Michael Schimerlik, and Dr. Claudia Maier for their support and academic
Application of modern NMR techniques to structure elucidation of bioactive natural products from tunicates

Creator:

Sikorska, Justyna

Abstract:

Recent developments in NMR hardware have extended the reach of natural products chemists to structure elucidation of compounds isolated on a nanomolar scale. In parallel with advances in hardware new NMR techniques for structure elucidation have evolved, e.g. quantitative NOEs, residual dipolar couplings (RDCs)and diffusion-ordered spectroscopy (DOSY). The application of...

Resource Type:

Dissertation