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Filtering by: Advisor Whanger, Philip D. Remove constraint Advisor: Whanger, Philip D. Academic Affiliation Environmental and Molecular Toxicology Remove constraint Academic Affiliation: Environmental and Molecular Toxicology

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  • Characterization of rodent selenoprotein W promoter

    Creator:
    Amantana, Adams
    Abstract:
    Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
    Resource Type:
    Dissertation
    Full Text:
    Selenoprotein W Promoter Abstract approved: Philip D. Whanger Rat selenoprotein W (SeW) promoter activity was

  • Selenoprotein W : Purification and characterization of its interaction with calmodulin

    Creator:
    Bauman, Andrew Thomas
    Abstract:
    Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
    Resource Type:
    Dissertation
    Full Text:
    : Purification and Characterization of its Interaction with Calmodulin. Abstract approved: Philip D. Whnger