Index Catalog // ScholarsArchive@OSU

Creator:: Katchamart, Sirinmas
Abstract:: Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...
Resource Type:: Dissertation
Full Text:: assistance and Angsana Phoosuntisumpunth, Dr. Siriporn Pipatsatayanuwong, Dr. Mei-Fei Yueh, Marilyn

Creator:: Leibelt, Dustin A.
Abstract:: Indole-3-carbinol (I3C) is a naturally occurring plant alkaloid, found in significant concentrations in cruciferous vegetables such as broccoli and Brussels sprouts. I3C is an unstable compound that undergoes rapid oligomerization in an acidic environment to form higher order condensation products (I3C-ACPs), such as 3-3'-diindolylmethane (DIM). Both I3C and DIM are...
Resource Type:: Dissertation
Full Text:: Larson-Su, Dr. Aram Oganesian, Dr. Mei-Fei Yueh, Dr. Sirinmas Katchamart, Dr. Margaret Pratt, Susan

Creator:: Singh, Priti B.
Abstract:: Multiple drug resistance (MDR) Tuberculosis (TB), leads to increased use of “second-line” drugs; one of the most effective is ethionamide (ETA). ETA is a prodrug metabolized by a mycobacterial flavin-containing monooxygenase (EtaA) as well human flavin-containing monooxygenases (FMOs). Of the five functional FMOs of humans, FMOs 1, 2, and 3...
Resource Type:: Masters Thesis
Full Text:: functionally active enzyme in human lung (Yueh et al. 1997). Approximately 26% of African-, 7% of Puerto

Creator:: Shilling, Adam D.
Resource Type:: Dissertation
Full Text:: Katchamart, Dr. Mei-Fei Yueh, Dr. Shelley Larsen-Su and Dustin Leibelt who were so unselfish in their time

Creator:: Haggard, Derik
Abstract:: There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
Resource Type:: Dissertation

ScholarsArchive@OSU