Index Catalog // ScholarsArchive@OSU

Start Over

Filtering by: Creator Alioua, Malek Academic Affiliation Microbiology

Organelle trafficking of chimeric ribozymes and genetic manipulation of mitochondria

Creator:

Val, Romain, Wyszko, Eliza, Valentin, Clarisse, Szymanski, Maciej, Cosset, Anne, Alioua, Malek, Dreher, Theo W., Barciszewski, Jan, and Dietrich, Andre

Abstract:

With the expansion of the RNA world, antisense strategies have become widespread to manipulate nuclear gene expression but organelle genetic systems have remained aside. The present work opens the field to mitochondria. We demonstrate that customized RNAs expressed from a nuclear transgene and driven by a transfer RNA-like (tRNA-like) moiety...

Resource Type:

Article

Full Text:

Szymanski2, Anne Cosset1, Malek Alioua1, Theo W. Dreher3, Jan Barciszewski2 and André Dietrich1