Index Catalog // ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: Costimulation and Adjuvants in the Development of T Cell Effector and Memory Responses. Abstract approved

Silencing of Agrobacterium tumefaciens T-DNA oncogenes by cosuppression

Creator:: Lee, Hyewon
Abstract:: We have developed crown-gall resistant transgenic plants capable of suppressing Agrobacterium tumefaciens T-DNA oncogenes. Crown gall tumors result from overproduction of auxin and cytokinin in plant cells transformed by A. tumefaciens. High phytohormone levels result from expression of two auxin biosynthetic genes, tryptophan monooxygenase (iaaM) and indole acetamide hydrolase (iaaH),...
Resource Type:: Masters Thesis
Full Text:: Silencing of Agrobacterium tumefaciens T-DNA oncogenes by

Comparing Sediment Microbial Communities of Arctic Beaver Ponds to Tundra Lakes and Streams

Creator:: Shannon, Kelly
Abstract:: In recent decades the habitat of North American beaver (Castor canadensis) has expanded from boreal forests into pan-Arctic tundra ecosystems. It is unknown how the advance of beavers into Arctic watersheds will impact microbial communities responsible for the mineralization of organic matter (OM), which has implications for carbon cycling. To...
Resource Type:: Masters Thesis
Full Text:: duplicate so that T. thermophilus represented 0.5% (first replicate) and 1.0% (second replicate) of total

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

Creator:: Schuster, Corbin J.
Abstract:: Pseudoloma neurophilia is the most common pathogen reported in zebrafish (Danio rerio) research facilities and is an important threat to the zebrafish model. This microsporidian parasite can cause clinical disease, but more importantly is a causative agent of non-protocol induced variation in research. Studies utilizing infected zebrafish, could potentially confound...
Resource Type:: Dissertation
Full Text:: ., Hayward, S., Miller, T. L., & Jerry, D. R. (2017). Use of environmental DNA (eDNA) and water quality data

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Creator:: Neal, James T., Peterson, Tracy S., Kent, Michael L., and Guillemin, Karen
Abstract:: Infection with Helicobacter pylori is a major risk factor for the development of gastric cancer, and infection with strains carrying the virulence factor CagA significantly increases this risk. To investigate the mechanisms by which CagA promotes carcinogenesis, we generated transgenic zebrafish expressing CagA ubiquitously or in the anterior intestine. Transgenic...
Resource Type:: Article
Full Text:: activation in a transgenic zebrafish model James T. Neal1,*, Tracy S. Peterson2,‡, Michael L. Kent2 and Karen

Preventing crown gall disease using oncogene silencing or VirE1-expressing transgenics

Creator:: Humann, Jodi L.
Abstract:: Crown gall disease is caused by the ubiquitous soil bacterium Agrobacterium tumefaciens which transfers a portion if DNA (T-DNA) into the plant cell. Preventing infection by using the biocontrol strain Agrobacterium radiobacter K84 is currently the only defense for crown gall. Two different resistance strategies were examined in this work....
Resource Type:: Dissertation
Full Text:: a portion if DNA (T-DNA) into the plant cell. Preventing infection by using the biocontrol strain

Fecal Bacteroidetes host distributions and environmental source tracking

Creator:: Dick, Linda K.
Abstract:: Contamination of recreational and shellfish waters with fecal pollution is a major water quality issue with associated economic impacts and human health risks. Reliable fecal source identification and rapid, quantitative analyses are essential components of risk assessment. Enteric bacteria that are endemic to specific hosts have a potential role as...
Resource Type:: Dissertation
Full Text:: the host species using Terminal Restriction Fragment Length Polymorphisms (T-RFLP). Clones

Anaerobic biodegradation of the cyclic nitramines, RDX and HMX, by ovine ruminal microbes

Creator:: Eaton, Hillary L.
Abstract:: Cyclic nitramines released into all environmental compartments through anthropogenic activities are toxic and possibly carcinogenic and mutagenic. Soils on military ranges, located throughout the world in various climatic regions and close to human activities, are especially susceptible to cyclic nitramine contamination. The properties of soils on military ranges will directly...
Resource Type:: Dissertation
Full Text:: help to stay on track and time in listening to me. I also owe my sincere gratitude to Dr. Mary Burke

Comparison of fixatives and fixation time for PCR detection of Mycobacterium in zebrafish Danio rerio

Creator:: Peterson, Tracy S., Kent, Michael L., Ferguson, Jayde A., Watral, Virginia G., and Whipps, Christopher M.
Abstract:: Mycobacteriosis is a common disease of laboratory zebrafish Danio rerio. Different infection patterns occur in zebrafish depending on mycobacterial species. Mycobacterium marinum and M. haemophilum produce virulent infections associated with high mortality, whereas M. chelonae is more widespread and is not associated with high mortality. Identification of mycobacterial infections to...
Resource Type:: Article
Full Text:: DNA from tissues (Tokuda et al. 1990, Greer et al. 1991). Fixative formulations, especially those

A molecular study of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus

Creator:: Chiou, Pinwen Peter
Abstract:: The role of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus (IHNV) was studied at the molecular level. The expression of the viral genes at the protein and RNA level, and their cellular localization, were characterized to further our understanding of viral pathogenesis. The pathogenic effect of individual...
Resource Type:: Dissertation
Full Text:: older than one year (Yasutake, 1978; Burke and Grischowsky, 1984; Traxler, 1986; Banner et al., 1991

ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Silencing of Agrobacterium tumefaciens T-DNA oncogenes by cosuppression

Comparing Sediment Microbial Communities of Arctic Beaver Ponds to Tundra Lakes and Streams

Expanding Diagnostic Assays for Pseudoloma neurophilia & Description of the Progression of Infection in Adult Zebrafish Populations

H. pylori virulence factor CagA increases intestinal cell proliferation by Wnt pathway activation in a transgenic zebrafish model

Preventing crown gall disease using oncogene silencing or VirE1-expressing transgenics

Fecal Bacteroidetes host distributions and environmental source tracking

Anaerobic biodegradation of the cyclic nitramines, RDX and HMX, by ovine ruminal microbes

Comparison of fixatives and fixation time for PCR detection of Mycobacterium in zebrafish Danio rerio

A molecular study of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus

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