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Filtering by: Creator Hase, Claudia C. Remove constraint Creator: Hase, Claudia C. Academic Affiliation Microbiology Remove constraint Academic Affiliation: Microbiology

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  • Investigating Vibrio parahaemolyticus interactions with the Pacific oyster, Crassostrea gigas

    Creator:
    Aagesen, Alisha M.
    Abstract:
    Vibrio parahaemolyticus is a Gram-negative, halophilic, human pathogenic bacterium ubiquitous in the marine environment. Like many Vibrio species, V. parahaemolyticus commonly associates with shellfish, particularly oysters. Ingestion of a raw or under cooked oysters contaminated with V. parahaemolyticus can cause gastroenteritis, which is typically self-limiting and rarely causes death. Globally,...
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________ Claudia C. Häse Vibrio parahaemolyticus is a Gram-negative, halophilic, human

  • Molecular and genetic assessment of selected antiporters and methyl-accepting chemotaxis proteins in Vibrio cholerae

    Creator:
    Quinn, Matthew J.
    Abstract:
    The pathogen Vibrio cholerae uses cations as a primary currency of virulence and environmental persistence, using gradients of those cations to move, acquire nutrients, and control virulence gene expression. An understanding of the overlapping roles of bioenergetics and chemotaxis in the virulence and environmental survival of V. cholerae issues from...
    Resource Type:
    Dissertation
    Full Text:
    C. Häse The pathogen Vibrio cholerae uses cations as a primary currency of virulence and

  • Identification of an aerotaxis transducer in Vibrio cholerae

    Creator:
    Boin, Markus A.
    Abstract:
    The ability to move towards favorable environmental conditions, called chemotaxis, is common among motile bacteria. In particular aerotaxis has been extensively studied in Escherichia coli. Three putative aer gene homologs were identified in the V. cholerae genome designated VCAer-1 (VC0512) VCAer-2 (VCA0658), and VCAer-3 (VCA0988). Deletion analyses indicated that only...
    Resource Type:
    Masters Thesis
    Full Text:
    : Claudia Häse The ability to move towards favorable environmental conditions, called chemotaxis

  • Comparative genomics of Vibrio and characterizing microbial communities at a shellfish hatchery

    Creator:
    Delgado, Hanna
    Abstract:
    Vibrio bacteria are commonly found in freshwater, marine, and estuarine environments. Members of this genus can exist in commensal relationships with marine animals or as planktonic bacteria, however, they are well known for their roles as pathogens towards humans and animals. In this dissertation, I investigated aspects of host-bacteria relationships...
    Resource Type:
    Dissertation
    Full Text:
    /10.1186/s12864-020-6471-x Elston, R., Hasegawa, H., Humphrey, K., Polyak, I., Häse, C., 2008. Re

  • Developing a system of mutagenesis in Francisella tularensis LVS

    Creator:
    Flax, Lindsay A.
    Abstract:
    Francisella tularensis is a gram-negative facultative intracellular coccobacillus that primarily infects macrophages. The causative agent of tularemia, this bacterium is considered among the most infectious organisms known, requiring fewer than ten organisms to cause disease. Although ubiquitous in nature, transmission to humans is rare but can occur via insect bites,...
    Resource Type:
    Masters Thesis
    Full Text:
    throughout the years. Special thanks to Dr. Claudia Häse for the hours spent discussing my project

  • Clostridium perfringens sporulation and gliding motility

    Creator:
    Huang, I-Hsiu
    Abstract:
    Clostridium perfringens type A isolates, an anaerobic enterotoxigenic spore forming bacterium, are the third leading cause of food-borne disease in the United States. Factors that contribute to the virulence of C. perfringens include the ability of the bacterium to form heat resistant spores and to produce an enterotoxin (CPE). Although...
    Resource Type:
    Dissertation
    Full Text:
    . Also many thanks to my committee members, Dr. Luiz Bermudez, Dr. Claudia Hase, Dr. Emily Ho, Dr. Dan

  • Characterization of Sporulation and Germination Genes in Clostridium perfringens

    Creator:
    Talukdar, Prabhat Kumar
    Abstract:
    Clostridium perfringens is a Gram-positive, anaerobic, spore-forming bacterium that can produce as many as 17 different toxins and are responsible to cause a wide array of gastrointestinal (GI) and histotoxic diseases in humans and animals. As individual strains produce a subset of these toxins, C. perfringens strains can be classified...
    Resource Type:
    Dissertation
    Full Text:
    . Daniel Rockey, Dr. Claudia Hase and Dr. Kathy O’Reilly for serving as my committee members. I am

  • New Insights into the Molecular Mechanism of Clostridium perfringens Spore Germination

    Creator:
    Banawas, Saeed S.
    Abstract:
    C. perfringens is a spore-forming, gram-positive, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses. Interestingly, these two major diseases are...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Claudia Häse and Dr. Jean Hall, who offered guidance and support. I would like to thank all

  • Quorum sensing gene regulation in Pseudomonas aeruginosa

    Creator:
    Gupta, Rashmi
    Abstract:
    Pseudomonas aeruginosa is an opportunistic human pathogen that infects immunocompromised individuals such as those suffering from burns or the genetic disorder cystic fibrosis. This organism utilizes a cell-cell communication mechanism known as quorum sensing (QS) to coordinate virulence gene expression and biofilm formation. It has three interconnected QS systems, namely...
    Resource Type:
    Dissertation
    Full Text:
    . Claudia Häse, and Dr. Taifo Mahmud for their commitment and interest in my work and for useful

  • NhaP1 is a K+(Na+)/H+ antiporter required for growth and internal pH homeostasis of Vibrio cholerae at low extracellular pH

    Creator:
    Quinn, Matthew J., Resch, Craig T., Sun, Jonathan, Lind, Erin J., Dibrov, Pavel, and Hase, Claudia C.
    Abstract:
    Vibrio cholerae has adapted to a wide range of salinity, pH and osmotic conditions, enabling it to survive passage through the host and persist in the environment. Among the many proteins responsible for bacterial survival under these diverse conditions, we have identified Vc-NhaP1 as a K+(Na+)/H+ antiporter essential for V....
    Resource Type:
    Article
    Full Text:
    . Resch,3 Jonathan Sun,1 Erin J. Lind,2 Pavel Dibrov3 and Claudia C. Häse1,2 Correspondence Claudia C