Index Catalog // ScholarsArchive@OSU

The Genome of Pseudomonas fluorescens Strain R124 Demonstrates Phenotypic Adaptation to the Mineral Environment

Creator:: Barton, Michael D., Petronio, Michael, Giarrizzo, Juan G., Bowling, Bethany V., and Barton, Hazel A.
Abstract:: Microbial adaptation to environmental conditions is a complex process, including acquisition of positive traits through horizontal gene transfer or the modification of existing genes through duplication and/or mutation. In this study, we examined the adaptation of a Pseudomonas fluorescens isolate (R124) from the nutrient-limited mineral environment of a silica cave...
Resource Type:: Article
Full Text:: . Barton, Michael Petronio, Juan G. Giarrizzo, Adaptation to the Mineral Environment Strain R124

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Creator:: Sexton, David
Abstract:: Cooperative behaviors in bacteria are increasingly appreciated for their relevance to microbial ecology and utility as model systems for social evolution. One example is the secretion of siderophores, a structurally diverse group of compounds that chelate extracellular iron. Siderophore production is considered cooperative because the benefits can be shared with...
Resource Type:: Dissertation
Full Text:: , creating regulatory hierarchies that further refine the response to iron limitation (Cornelis et al

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

Creator:: Chinison, Jessica J.
Abstract:: Cases of pulmonary diseases caused by Mycobacterium avium complex (MAC) have increased over the years and have become a major health concern in Europe, Asia, and the United States. MAC, comprised of M. avium species and M. intracellulare, are found everywhere in the environment: in water sources and the soil....
Resource Type:: Masters Thesis
Full Text:: secretion systems and disease.” Clin Microbiol Rev 20(4): 535-549. Cornelis, G. R., A. Boland, A. P

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation

Uncovering the mechanism of IL-4-mediated T cell survival

Creator:: Moscibrocki, Cathleen M.
Abstract:: Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
Resource Type:: Masters Thesis

Preventing crown gall disease using oncogene silencing or VirE1-expressing transgenics

Creator:: Humann, Jodi L.
Abstract:: Crown gall disease is caused by the ubiquitous soil bacterium Agrobacterium tumefaciens which transfers a portion if DNA (T-DNA) into the plant cell. Preventing infection by using the biocontrol strain Agrobacterium radiobacter K84 is currently the only defense for crown gall. Two different resistance strategies were examined in this work....
Resource Type:: Dissertation
Full Text:: , IWD2 Oe H,d,oLases' (wA B G c D ) VG 0WE2U ' WA Phenolics, sugars, and acidity from wounded plant

The Social Interactions of Pseudomonas aeruginosa

Creator:: Smith, Parker
Abstract:: Pseudomonas aeruginosa is a ubiquitous environmental microbe, opportunistic pathogen, and a highly social organism. P. aeruginosa utilizes a wide array of cooperative behaviors to adapt to the environmental conditions around it. These behaviors include quorum sensing (QS), a form a cell-to-cell signaling that coordinates the expression of secreted products in...
Resource Type:: Dissertation
Full Text:: proportion of cheaters is high (right). (G) Non-social adaptation. Mutations in cooperator cells allow

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Creator:: Simon, Benjamin E.
Abstract:: Several systems were examined for the production and delivery of recombinant vaccines for fish. C. crescentus was employed to produce a fragment of the IHNV glycoprotein. When administered by injection to 0.5 gram rainbow trout (Oncorhynchus mykiss), one of the fusion proteins (184 amino acids of the IHNV glycoprotein fused...
Resource Type:: Dissertation
Full Text:: fish (100-300 g) (Traxier et al., 1999). Yersinia ruckeri Y. ruckeri is the causative agent of

Chromatophores as cell-based biosensors for the detection of chemically and biologically toxic substances

Creator:: Dukovcic, Stephanie R.
Abstract:: Cell-based biosensors are function-based detectors that use the physiological response of a living cell to sense biologically stimulating agents. This emerging technology extends the application of current detection methods by reporting on the toxicity of a sample and the potential to cause disease. Previously, Betta splendens erythrophores have been described...
Resource Type:: Dissertation
Full Text:: (171, 272, 276, 279). Pigment aggregation occurs in response to G-protein coupled receptor binding

ScholarsArchive@OSU

The Genome of Pseudomonas fluorescens Strain R124 Demonstrates Phenotypic Adaptation to the Mineral Environment

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Establishment of an in vitro System for Studying Mycobacterium avium Protein Secretion

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Uncovering the mechanism of IL-4-mediated T cell survival

Preventing crown gall disease using oncogene silencing or VirE1-expressing transgenics

The Social Interactions of Pseudomonas aeruginosa

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Chromatophores as cell-based biosensors for the detection of chemically and biologically toxic substances

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