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Filtering by: Creator Shii, Chou Tou Academic Affiliation Pharmaceutical Chemistry

Synthesis and structure-activity relationships of some 4-substituted pyrazole and isoxazole inhibitors of liver alcohol dehydrogenase ; The use of molecular connectivity in the multivariate classification of drug molecules

Creator:

Henry, Douglas R.

Abstract:

In a two part thesis, studies were made of two different types of structure-activity relationships. The first part consists of the synthesis and biological evaluation of a number of 4-substituted pyrazoles and isoxazoles as inhibitors of liver alcohol dehydrogenase. In an effort to better define the steric and electronic effects...

Resource Type:

Dissertation