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Filtering by: Academic Affiliation Physics Creator Sun, Bo

Understanding metastatic growth through the traction force of human breast cancer cells

Creator:

Dinh, Theresa, Kim, Jihan, and Sun, Bo

Abstract:

Cancer is a hard disease to control because of its ability to spread to different parts of the body. Cancer cells can spread out from a primary tumor to distant organs which gives rise to new cancer cell colonies and more tumors over time. This process is known as metastasis...

Resource Type:

Poster
Three-Dimensional Reflectance Traction Microscopy

Creator:

Kim, Jihan, Jones, Christopher A. R., Groves, Nicholas Scott, and Sun, Bo

Abstract:

Cells in three-dimensional (3D) environments exhibit very different biochemical and biophysical phenotypes compared to the behavior of cells in two-dimensional (2D) environments. As an important biomechanical measurement, 2D traction force microscopy can not be directly extended into 3D cases. In order to quantitatively characterize the contraction field, we have developed...

Resource Type:

Article
A Novel Approach to Line Detection using Image Integration Method

Creator:

Lin, Daniel and Sun, Bo

Abstract:

- Collagen fibers are found in 25% of the whole body protein content. They are highly adhesive to cells and can be used as scaffold proteins that can promote cell growth and be used to capture cells. - In our lab, we use collagen to capture cancer cells in order...

Resource Type:

Poster
Network Characteristics of Collective Chemosensing

Creator:

Sun, Bo, Duclos, Guillaume, and Stone, Howard A.

Abstract:

The collective chemosensing of nonexcitable mammalian cells involves a biochemical network that features gap junction communications and heterogeneous single cell activities. To understand the integrated multicellular chemosensing, we study the calcium dynamics of micropatterned fibroblast cell colonies in response to adenosine triphosphate (ATP) stimulation. We find that the cross-correlation function...

Resource Type:

Article