Index Catalog // ScholarsArchive@OSU

Pharmacokinetic modeling of theophylline and dyphylline and pharmacodynamics of ibuprofen input rate on antipyresis

Creator:: Stevens, Ruth E.
Abstract:: Pharmacokinetic parameters for theophylline and dyphylline were evaluated in horse cerebrospinal fluid (csf) and plasma. Pharmacokinetic parameters did not differ significantly (p > 0.05) at the same dose for either drug when administered alone or concomitantly. Theophylline and dyphylline penetrate horse csf to produce approximately 1/2 the concentrations found in...
Resource Type:: Dissertation
Full Text:: and pharmacodynamics of ibuprofen input rate on antipyresis AN ABSTRACT OF THE THESIS OF Ruth E

New product formulations, pharmacokinetics and bioavailability of dyphylline

Creator:: Chang, Shyi-Feu
Abstract:: Product formulation and in vitro dissolution characteristics of sustained-release chewable tablet dosage forms are presented in chapter one of this thesis. In vivo single dose and multiple dose studies of two sustained-release formulations as well as one conventional dyphylline formulation are described in chapter two. The pharmacokinetics of dyphylline following...
Resource Type:: Dissertation
Full Text:: which diffusion occurs through channels: Q= [DE /T(2A -E Cs)CstJl /2 where Q is the amount of drug

Prolonged duration of action of dyphylline through prodrugs

Creator:: Panomvana, Duangchit
Resource Type:: Dissertation
Full Text:: . Redacted for privacyAbstract approved: ?'Dr. James W. Ayres A series of four diesJrs and four monoesters

New product formulations and pharmacokinetics of acetaminophen

Creator:: Borin, Marie T.
Resource Type:: Dissertation
Full Text:: ). 201 206 207 208 209 210 211 212 213 214 Table Page III.6b E . 1 Pharmacokinetic

Comparative pharmacokinetic studies of dyphylline and some dyphylline prodrugs

Creator:: Huang, Hua-pin
Abstract:: Dyphylline is an analog of theophylline and the latter is the most popular member of the methylxanthine family in use for the treatment of asthma. Although dyphylline is devoid of some problems associated with theophylline, a reported short half-life has made it's clinical usefulness limited. To avoid this problem a...
Resource Type:: Masters Thesis
Full Text:: ....- v,....- ,-...- Dr. James W. Ayre i Dyphylline is an analog of theophylline and the latter is the

Chelating agents in the drug dosage design of iron preparations

Creator:: Ghannam, Musa
Abstract:: The role of iron in the body is well known for it is a component of hemoglobin, myoglobin, cytochrome, enzyme catalase and peroxidase. Iron deficiency anemia is widespread among vulnerable groups in industrialized societies and in the general population of tropical developing areas. In the United States there are ten...
Resource Type:: Masters Thesis
Full Text:: , Redacted for Privacy / Dr. James R. Ayre'V Abstract approved: The role of iron in the body is well known

Formulation studies of lactic acid-producing bacteria for oral administration

Creator:: Liou, Yow-Hwa Grace
Abstract:: Effects of lactobacilli in enteric coated capsules were studied in piglets (Chapter I). Lactobacillus acidophilus and Lactobacillus bulgaricus isolated from a commercial product were formulated in capsules, enteric coated, and then given to both Escherichia coli-challenged and unchallenged baby pigs. Decreased incidence and severity of diarrhea, and decreased weight deceleration...
Resource Type:: Dissertation
Full Text:: ACKNOWLEDGEMENTS I would like to thank my major professor, Dr. James W. Ayres and Dr. William E. Sandine for

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Creator:: Tavipatana, Wattanaporn
Abstract:: Pharmacokinetics of theophylline and N-7 substituted theophylline in rabbits when administered alone and in various combinations were investigated. This thesis has four chapters dealing with etophylline and theophylline; proxyphylline and theophylline; dyphylline and theophylline; and etophylline, proxyphylline and dyphylline pharmacokinetics when administered concomitantly. All chapters are interrelated. Each chapter has...
Resource Type:: Masters Thesis
Full Text:: (E(xi - M)2/(N - 1))/ e (S.D./Mean) x 100 * 0.693 /BMean Table I.2a Pharmacokinetic Parameters for

Pharmacokinetics of dyphylline after administration of prodrugs in rabbits and pigs

Creator:: Huang, Hua-pin
Abstract:: Dyphylline is an analogue of theophylline and the latter is the most popular member of the methyixanthine family in use for the treatment of asthma. Although dyphylline is devoid of some problems associated with theophylline, a reported short half-life for dyphylline (2.1 hours) has made its clinical usefulness limited. In...
Resource Type:: Dissertation
Full Text:: . Maney, J. W. Jones, E. G. Gross and H. M. Korns, J. Am. Pharm. Assoc. 35, 266 (1946). 3. J. D. McColl

The effect of food and tablet age on the relative bioavailability and pharmacodynamics of two tolbutamide products

Creator:: Olson, Stephen Carl
Abstract:: The relative bioavailability and pharmacodynamics of tolbutamide from two different commercially available tablet products has been evaluated in healthy subjects in a single dose cross over study. Products were aged by exposing tablets to 98% relative humidity for 3 days at ambient temperature which was found to differentially affect both...
Resource Type:: Dissertation
Full Text:: PRODUCTS Abstract Approved: Redacted for Privacy James W. Ayres, PhiDO The relative bioavailability and

ScholarsArchive@OSU

Pharmacokinetic modeling of theophylline and dyphylline and pharmacodynamics of ibuprofen input rate on antipyresis

New product formulations, pharmacokinetics and bioavailability of dyphylline

Prolonged duration of action of dyphylline through prodrugs

New product formulations and pharmacokinetics of acetaminophen

Comparative pharmacokinetic studies of dyphylline and some dyphylline prodrugs

Chelating agents in the drug dosage design of iron preparations

Formulation studies of lactic acid-producing bacteria for oral administration

Pharmacokinetics of theophylline and it's N-7 derivatives in rabbits

Pharmacokinetics of dyphylline after administration of prodrugs in rabbits and pigs

The effect of food and tablet age on the relative bioavailability and pharmacodynamics of two tolbutamide products

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search