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Filtering by: Creator Bahr, Frank Advisor Barofsky, Douglas F.

Proteomic approach to the analysis of DNA-binding proteins using mass spectrometry

Creator:

Stapels, Martha Degen

Abstract:

In proteomic studies, separate experimental protocols have been necessary to identify proteins, determine their function, and predict their three-dimensional structure. In this study, a function-based separation of proteins was conceived to fractionate proteins prior to enzymatic digestion. In the initial demonstration of this technique, a DNA substrate was used to...

Resource Type:

Dissertation

Full Text:

Variation on the Free-Jet Theme," JPhys Chem, 88:4451-4459. 10. Karas, M., Bachmann, D., Bahr, U., and
Chlordecone pretreatment promoted subcellular distribution of scavenger receptor class B type II to murine hepatic microsomes ; mass spectrometry detected hepatic soluble cholesterol binding proteins and comparison of protein iTRAQ ratios using ESI QTOF and MALDI TOF/TOF

Creator:

Scheri, Richard C.

Abstract:

Chlordecone belongs to the class of persistent organochlorine pesticides that are remarkably resistant to environmental degradation. Even though their use was banned in the United States in 1978, these compounds can still be detected in both humans and wildlife throughout the world. Previous work has shown that the pretreatment of...

Resource Type:

Dissertation