Index Catalog // ScholarsArchive@OSU

Creator:: Li, Xin
Abstract:: This dissertation is separated into two parts according to the two major distinct research projects. In Part I, the full account of synthetic studies toward C10-functionalized lycopodium alkaloids is described. In Part II, the detailed discussion on the exploration of the Pummerer cyclization methodology and its application to the total...
Resource Type:: Dissertation
Full Text:: (relative to the sulfoxide). Two sets of the divergent reaction conditions (TFAA, 1,2-DCE, 4 h; then add

Creator:: Veerasamy, Nagarathanam
Abstract:: The enantioselective total synthesis of quinolizidine-containing natural product cermizine D and formal syntheses of senepodine G and cermizine C has been achieved. These natural products are members of the lycopodium alkaloids, which have attracted significant attention due to their exciting biological activities and the diverse structural scaffolds. Key steps in...
Resource Type:: Dissertation
Full Text:: 25 °C 63% (2 steps) N H O Me2CuLi, BF3•Et2O THF, -78 to 25 °C 80%N H O MeMgBr (4 equiv

Creator:: Saha, Mrinmoy
Abstract:: Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
Resource Type:: Dissertation
Full Text:: lycodine (1.2) NH N fawcettimine (1.3) phlegmarine (1.4) NH N N O OH H ! 4! Figure 1.2

Creator:: Schwartz, Johanna Perkins
Abstract:: A Diels-Alder approach to biaryls (DAB) has been applied towards the synthesis of highly substituted, programmable biaryl templates. Tri- and tetra-ortho-substituted biaryls can be produced in just three to four steps from commercially available materials utilizing the Diels-Alder [4+2] cycloaddition. The methods described herein will illustrate the ability of mono...
Resource Type:: Dissertation
Full Text:: 4 Bu3Sn MeO Cl Pd2(dba)3 (1.5 mol%) P(t-Bu)3, (6 mol%) 2.2 eq CsF, dioxane 100˚C, 94% OMe N H

Creator:: McIntosh, Melissa Luana
Abstract:: Nitroaromatic compounds have important chemical applications and can be found in nature as pollution sources. Synthetic nitroaromatic compounds have been used in a variety of materials including explosives, pharmaceuticals, dyes, plastics, and pesticides. These compounds can find their way into the environment through normal or improper disposal methods. Poly-aromatic compounds...
Resource Type:: Masters Thesis
Full Text:: Through Reduced Nitroaromatic HO R O + H N R O 1.1.16 1.1.17 1.1.18 1.1.19 NEt3 CH2Cl2 (Eq. 4

ScholarsArchive@OSU