Search Constraints

Start Over
Filtering by: Alternative title ssim EC 923 Remove constraint Alternative title ssim: EC 923 Advisor Gerwick, William H. Remove constraint Advisor: Gerwick, William H.

Search Results

  • The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

    Creator:
    Lopez, Albert
    Abstract:
    The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
    Resource Type:
    Masters Thesis
    Full Text:
    subtilus; Ec = Escherichia coli, Pa = Pseudomonas aeruginosa; Ca = Candida albicans. The plates were

  • Novel icosanoids from the red marine alga Farlowia mollis

    Creator:
    Solem, Michele Lee
    Abstract:
    Farlowia mollis is a marine red alga that grows in the intertidal region along the coast of Oregon. We began studying the chemistry of this alga after a survey of Oregon seaweeds revealed possibly interesting chemistry and antimicrobial activity in its crude organic extract. Over the past three years the...
    Resource Type:
    Masters Thesis

  • Structure elucidation and biosynthetic investigations of marine cyanobacterial secondary metabolites

    Creator:
    Nogle, Lisa Marie
    Abstract:
    This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
    Resource Type:
    Dissertation
    Full Text:
    Doublet DHiv Dihydroxyisovaleric acid DMSO Dimethylsulfoxide EC Effective Concentration EtOAc Ethyl

  • Novel oxylipins and other bioactive metabolites from marine algae

    Creator:
    Nagle, Dale George
    Abstract:
    I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
    Resource Type:
    Dissertation
    Full Text:
    DMSO Dimethylsulfoxide EC Effective Concentration EI Electron Impact EtOAc Ethyl Acetate FAB Fast