Index Catalog // ScholarsArchive@OSU

Creator:: Marquez, Brian L.
Abstract:: This thesis is an account of my explorations into the field of natural products chemistry. These investigations led to the discovery of several novel secondary metabolites isolated from the marine cyanobacterium Lyngbya majuscula. In addition, biosynthetic investigations were undertaken using stable isotope-labeled precursors. The dominant role that NMR spectroscopy plays...
Resource Type:: Dissertation
Full Text:: Cyanobactenal Natural Products: Development and Application of New NMR Methods. Abstract approved: William H

Creator:: Nannini, Christopher J.
Abstract:: Marine organisms produce a variety of secondary metabolites for defense, communication, and reproduction. While these uses are essential for the organisms' survival, marine natural products have demonstrated their value to human society as well. Asian countries used algae for centuries to treat or prevent illnesses as wide-ranging as cough, gout,...
Resource Type:: Masters Thesis
Full Text:: from a Madagascar Collection of Lyngbya ma/uscula. Abstract approved William H. Gerwick Marine

Creator:: Ramaswamy, Aishwarya V.
Abstract:: Cyanobacteria are rich in biologically active secondary metabolites, many of which have potential application as anticancer or antimicrobial drugs or as useful probes in cell biology studies. A Jamaican isolate of the marine cyanobacterium, Lyngbya majuscula was the source of a novel antifungal and cytotoxic secondary metabolite, hectochlorin. The structure...
Resource Type:: Dissertation
Full Text:: Lyngbya maluscula Abstract approved: William H. Gerwick Cyanobacteria are rich in biologically active

Creator:: Nogle, Lisa Marie
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of thirteen new secondary metabolites, the isolation of over fifteen previously reported metabolites and the biosynthetic investigation of two additional cyanobacterial compounds. Two novel lipopeptides were identified from a Lyngbya majuscula and Schizothrix sp. assemblage...
Resource Type:: Dissertation
Full Text:: Biosynthetic Investigations of Marine Cyanobacterial Secondary Metabolites Abstract approved William H

Creator:: Sitachitta, Namthip
Abstract:: The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich in bioactive secondary metabolites. This dissertation describes the chemistry of L. majuscula collected from Grenada, Fiji and Papua New Guinea, and the biosyntheses of two L. majuscula metabolites, curacin A and barbamide. The chemical studies with a Grenada collection...
Resource Type:: Dissertation
Full Text:: ------------ William H. Gerwick The marine cyanobacterium Lyngbya majuscula has proven to be extraordinarily rich

Creator:: Proteau, Philip J.
Resource Type:: Dissertation
Full Text:: Marine Algae and a Photoprotective Sheath Pigment from Blue-Green Algae Abstract approved: William

Creator:: Bernart, Matthew W.
Abstract:: Following surveys of seaweeds in Oregon and the Caribbean, four algal species were selected for study on the basis of their crude extract biological activity or thin-layer chromatographic characteristics. Extracts were fractionated by normal phase chromatography, including high performance liquid chromatography (HPLC). Derivatives (methyl esters, acetates, and benzoates) of natural...
Resource Type:: Dissertation
Full Text:: Algae Abstract approved: Redacted for Privacy William H. Gerwick Following surveys of seaweeds in

Creator:: Nagle, Dale George
Abstract:: I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
Resource Type:: Dissertation
Full Text:: Bioactive Metabolites From Marine Algae Abstract approved: William H. Gerwick I have participated in a

ScholarsArchive@OSU