Index Catalog // ScholarsArchive@OSU

Environmental Transformations of Nanoparticles in Natural Water Systems using a Hydrophobic and Hydrophilic Dye Assay

Creator:: Turnquist, Macklin C.
Abstract:: Nanoparticles (NPs) are generally defined as particles <100 nanometers (nm) in size in one dimension. Despite increasing industrial usage of TiO2 NPs in sunscreens, cosmetics, and water remediation little is known of their environmental behavior. The primary goal of this research was to develop a rapid method for determining the...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Bryan Harper, Committee Member, representing Department of Environmental and Molecular

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

Creator:: Zhou, Zitao
Abstract:: Nanotechnology products have long since made their way to markets around the world increasing the concerns about whether nanomaterials pose a risk to our environment or health. It has been suggested that engineered nanomaterial (ENM) with broad applications and rapid commercialization need better risk assessment and regulation. However, the refinement...
Resource Type:: Masters Thesis
Full Text:: . Stacey Harper for her continuous encouragement and wise advice. Thanks to Bryan Harper’s great

Addressing the Risks of Nanoscale Polymers: Exposure, Behavior, and Toxicity

Creator:: Stine, Jared
Abstract:: Nanoscale polymers (including nanoplastics) are widely present through commerce and make their way into the environment. As the improper disposal of plastic waste leads to continued accumulation and degradation of plastic pollution, the presence of plastic particles less than 1 micron (μm) in size (nanoplastics) will increase. Heightened concern over...
Resource Type:: Dissertation
Full Text:: advisor Dr. Stacey Harper and Bryan Harper for being fantastic mentors, teachers, and guides during my

A Nano-sized Dose of Toxicology: Elucidating the Disconnect Between Nanomaterial Dosimetry and Biological Effects

Creator:: Slattery, Matthew R.
Abstract:: Nanotechnologies continue to permeate a multitude of industries, with diverse applications ranging from pesticides to fuel additives. The unusual behavior of nanomaterials that drives their innovation also complicates the job of toxicologists tasked with assessing their potential environmental and public health impacts. This dissertation investigates the underlying reasons for uncertainty...
Resource Type:: Dissertation
Full Text:: the dream alive. Bryan Harper, for never failing to produce a smile while preaching the cyclical

Novel Approaches to Evaluate the Environmental Impacts of Nanomaterials

Creator:: Wu, Fan
Abstract:: Numerous studies have shown that some nanomaterials are highly toxic to aquatic organisms and can potentially disrupt overall community health; however, current methods to evaluate the nanomaterials environmental impacts rarely consider the environmental realism or provide sufficient detail on the impact at the community level. Here we demonstrate three approaches...
Resource Type:: Dissertation
Full Text:: development as a scientist and researcher. I also would like to thank Bryan Harper especially, his

Addressing Persistent Challenges in Nanotoxicology Exposures : Techniques for in situ Characterization

Creator:: Crandon, Lauren E.
Abstract:: Nanoparticles (NPs), defined by their size (1-100 nm), are increasingly incorporated into commercial and industrial products due to their high surface area and unique properties. They can be designed for specific applications by manipulating composition, size, shape, and surface functionalization. As NP production and complexity increases, there is a need...
Resource Type:: Dissertation
Full Text:: years has made me a better scientist and person. I would also like to thank Bryan Harper, who was

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

Creator:: Meredith, Ailcea N.
Abstract:: The low risk and sustainable implementation of nanotechnology requires understanding how nanomaterial physicochemical properties influence their toxicity. Major drivers of toxicity need to be avoided while maximizing product efficacy so nanomaterials can be produced to best serve their applications and be of low risk when intentionally or unintentionally released into...
Resource Type:: Masters Thesis
Full Text:: . Meredith with advice from Stacey Harper and Bryan Harper. All experiments and statistical analysis were

Analyzing the use of the acellular DCFH assay as a means of determining oxidative stress induced in zebrafish embryos exposed to lanthanide oxide nanoparticles

Creator:: Engstrom, Arek
Abstract:: The ability of nanoparticles (NPs) to induce oxidative stress on organisms has been linked to NP cytotoxicity and genotoxicity for a variety of organisms. One proposed mechanism of this increased oxidative stress is the ability of NPs to generate reactive oxygen species (ROS). Due to the dynamic nature and small...
Resource Type:: Honors College Thesis
Full Text:: thanks to Dr. Stacey Harper, Bryan Harper, Lauren Crandon, and Lindsay Denluck for their continuous

The Stability, Toxicity, and Reactivity of Zero Valent Iron Nanoparticles

Creator:: Bulovsky, Hannah G.
Abstract:: Zero valent iron nanoparticles effectively remediate groundwater contaminants due to their catalytic properties and enhanced surface area. However, these properties contribute to particle agglomeration, decreasing their effectiveness. In this study, we examined the effect of two stabilizing agents (gum arabic (GA) and sodium carboxymethyl cellulose (CMC)) on particle stability, toxicity,...
Resource Type:: Honors College Thesis
Full Text:: team in Dr. Stacey Harper’s Nanotoxicology Laboratory and the laboratory manager Bryan Harper, Teresa

Studies on effect of stabilizers, chelators and inherent periodicity on nanoparticle antioxidant activity

Creator:: Zhou, Zheng
Abstract:: The level of reactive oxygen species (ROS) is tightly regulated in biological systems as overproduction can lead to oxidative stress and result in a number of diseases. Due to its negative effects, antioxidants are studied and used against ROS in medicine, pharmaceuticals and therapeutics. Because of issues with the uptake...
Resource Type:: Masters Thesis
Full Text:: nanoparticles Zheng Zhou§, Aaron C. Anderson#, Bryan J. Harper† and Stacey L. Harper†,‡,§,* §School of

ScholarsArchive@OSU

Environmental Transformations of Nanoparticles in Natural Water Systems using a Hydrophobic and Hydrophilic Dye Assay

An in silico Approach to Determine the Influence of Surface Chemical Properties on the Toxicity of Engineered Zinc Oxide Nanoparticles

Addressing the Risks of Nanoscale Polymers: Exposure, Behavior, and Toxicity

A Nano-sized Dose of Toxicology: Elucidating the Disconnect Between Nanomaterial Dosimetry and Biological Effects

Novel Approaches to Evaluate the Environmental Impacts of Nanomaterials

Addressing Persistent Challenges in Nanotoxicology Exposures : Techniques for in situ Characterization

Assessing the Impacts of Size, Structure, and Surface Chemistry on the Toxicity of Two High Production Organic Nanomaterials using the Embryonic Zebrafish Model

Analyzing the use of the acellular DCFH assay as a means of determining oxidative stress induced in zebrafish embryos exposed to lanthanide oxide nanoparticles

The Stability, Toxicity, and Reactivity of Zero Valent Iron Nanoparticles

Studies on effect of stabilizers, chelators and inherent periodicity on nanoparticle antioxidant activity

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