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Filtering by: Creator Luna, John Remove constraint Creator: Luna, John Advisor Loesgen, Sandra Remove constraint Advisor: Loesgen, Sandra

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A Dive into the Pacific Fish Microbiome: Exploration of Antibiotics from a Unique Ecosystem

Creator:

Austin, Molly C.

Abstract:

With the rise of resistant bacterial pathogens, currently prescribed antibiotics are rendered useless. In recent years, marine natural products (MNPs) have emerged as novel sources for drug leads. The ocean is a complex environment where marine animals cohabitate with many, and sometimes harmful microorganisms and viruses, but resist infections. Developed...

Resource Type:

Honors College Thesis

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1260 HPLC system using a Phenomenex Luna Prep 5u-C18(2), 100Å 250 mm x 21.2 mm column. Metabolites
Gene Expression, Structure Elucidation, and Bioactivity of Aspergillus Natural Products

Creator:

Neuhaus, George F.

Abstract:

The study of natural products (NPs) and their application has shaped humanity. Starting with the idea of using plants as medicine, it has now grown into the science of purifying and identifying organic molecules from nature to study their inherent biological activities. Understanding the molecular structures of NPs is the...

Resource Type:

Dissertation

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family offered endless support throughout my graduate career. I need to thank my parents, John and
Bioactivity Screening and Gene Activation Strategies in Fungi

Creator:

Coddington, Nathan C.

Abstract:

Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...

Resource Type:

Honors College Thesis
New Treatments for HIV and Cancer: Uncovering Bioactive Compounds from Small Molecule Sources

Creator:

Overacker, Ross D.

Abstract:

Small molecule drugs have been instrumental in our fight against diseases, beginning when some of the earliest ancient cultures used plant remedies to treat illnesses. More recently, the skill of isolating and characterizing the active ingredients within bioactive plants and microbial extracts has led to the isolation and design of...

Resource Type:

Dissertation

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Academic Affiliation

Chemistry2

Advisor

Loesgen, Sandra[remove]4

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 2018 to 2020

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Committee Member

McPhail, Kerry2
Neuhaus, George F.2
Beaudry, Chris1
Beaudry, Christopher1
Blakemore, Paul1
more Committee Members »

Creator

Austin, Molly C.1
Coddington, Nathan C.1
Neuhaus, George F.1
Overacker, Ross D.1

Contributor

Adpressa, Donovon1
Bruhn, Torsten1
Lee, Mi Kyung1
Loesgen, Sandra1
Mead, Matthew E.1
more Contributors »

Date

Date range begin – Date range end

Current results range from 2018 to 2020

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Decade

2020-20291
2010-20193

Degree Field

Chemistry4

Degree Level

Bachelor's2
Doctoral2

Degree Name

Doctor of Philosophy (Ph.D.)2
Honors Bachelor of Science (H.B.S.)2

Language

English [eng]4

License

All rights reserved3
Attribution 4.0 (CC BY 4.0)1

Non-Academic Affiliation

Oregon State University. Honors College2

Peer Reviewed

No4

Resource Type

Dissertation2
Honors College Thesis2

Rights Statement

In Copyright3
In Copyright - Educational Use Permitted1

Subject

Fungi1
Insertional mutagenesis1

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