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  • The Oregon Tooth Journey : developing a researched-centered community engagement project to improve childhood dental health and education throughout Oregon

    Creator:
    Cowles, Emily A.
    Abstract:
    Childhood tooth decay is a prevalent and concerning public health issue that is often misunderstood or dismissed. In Oregon specifically, over 50% of children have experienced at least one instance of tooth decay and these rates are even higher for marginalized communities such as children living in poverty, children of...
    Resource Type:
    Honors College Thesis
    Full Text:
    : ___________________________________________________________ Philip McFadden Childhood tooth decay is a prevalent and concerning public health issue that is

  • The Dental Fluoridation Potential of Drinking Water

    Creator:
    Renyer, Karissa N.
    Abstract:
    Water fluoridation is considered one of the top ten greatest health achievements of the twentieth century due to its effectiveness in reducing the prevalence of dental caries. However, despite extensive research on the subject, there is little information currently available about how the constituents of drinking water affect the uptake...
    Resource Type:
    Honors College Thesis
    Full Text:
    Philip McFadden Water fluoridation is considered one of the top ten greatest health

  • Automethylation : a response to enzyme aging

    Creator:
    Lindquist, Jonathan A.
    Abstract:
    This is the first study to explore the ability of an enzyme to recognize and repair spontaneous age-dependent damage to its own sequence. Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM) is known to repair damage that arises from a spontaneous isomerization of aspartyl and asparaginyl residues in other proteins during aging. As...
    Resource Type:
    Dissertation
    Full Text:
    approved: Philip N. McFadden This is the first study to explore the ability ofan enzyme to recognize

  • Biologically inspired biosensors from fish chromatophores

    Creator:
    Young, Jun
    Abstract:
    This thesis explores the feasibility of using melanophore-based biosensors from Oreochromis niloticus. Melanophores are one type of pigmented cell of the scales and fins of fish that respond in a motile fashion to a diverse range of stimuli. Fish scales were employed as the first step in determining the utility...
    Resource Type:
    Masters Thesis
    Full Text:
    Chromatophores Abstract approved: Philip N. McFadden This thesis explores the feasibility of using melanophore

  • Protein methylation at sites of blood vessel injury

    Creator:
    Weber, Darin J.
    Abstract:
    Blood vessel injury was found to release intracellular pools of protein D-aspartyl/L-isoaspartyl carboxyl methyltransferase (PIMT) into the extracellular milieu, where it became trapped. Trapped PIMT was able to utilize radiolabeled S-adenosyl-L-methionine (AdoMet) introduced into the circulation to methylate blood vessel proteins containing altered aspartyl residues specifically at the site of...
    Resource Type:
    Dissertation
    Full Text:
    Methylation at Sites of Blood Vessel Injury. Abstract approved: Philip N. McFadden Blood vessel injury was

  • The spatial resolution of information in a diffusive cytoplasm

    Creator:
    Sellers, Drew L.
    Abstract:
    Every cell is faced continuously with the task of transducing a vast number of external signals into appropriate intracellular responses. In mammalian cells, membrane bound receptors modulate the production of secondary messenger molecules, such as cyclic AMP (cAMP). Cell signaling through second messengers relies on the diffusion of such second...
    Resource Type:
    Dissertation
    Full Text:
    Information in a Diffusive Cytoplasm. Abstract approved: Philip N. McFadden Every cell is faced continuously

  • Incorporation of chromatophores into multi-cellular biosensors

    Creator:
    Preston, R. Ryan
    Abstract:
    Methodologies that detect biologically active substances have important potential applications for medical diagnostics, drug discovery, and chemical and biological anti-terrorism efforts. The wide spectrum of potential analytes that induce a physiological response dictates that novel techniques be developed to more rapidly screen and characterize agents that are more economical and...
    Resource Type:
    Dissertation
    Full Text:
    : Incorporation of Chromatophores into Multi-Cellular Biosensors. Abstract approved: Philip N. McFadden