Index Catalog // ScholarsArchive@OSU

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Creator:: Ryder, Matthew P.
Abstract:: While hydrophobic surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] (PEO-PPO-PEO) surfactant Pluronic® F108 are highly resistant to plasma protein adsorption, the antimicrobial peptide nisin has been observed to adsorb in multilayer quantities at such surfaces, and the PEO chains themselves suggested to inhibit nisin exchange by blood proteins. But...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Matthew P Ryder for the

Functionalization of Surfaces with Nisin in a Polyethylene Oxide Brush Layer

Creator:: Ryder, Matthew P.
Abstract:: Infections in hospitals account for over 100,000 deaths per year. These infections occur at the hospital from complications following bacterial adhesion to intravenous catheters, coronary stents and other implanted devices. Another common problem is protein adsorption to the surface of the device and subsequent blood clotting. Methods for combating these...
Resource Type:: Honors College Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Matthew P Ryder for the

Synthesis and anticoagulant function of heparin containing block copolymers on polystyrene microspheres

Creator:: Fry, Allyson Kaye
Abstract:: Contact of blood with the surfaces of synthetic materials is associated with spontaneous protein adsorption, initiating platelet aggregation, the coagulation cascade, and the eventual development of a stable clot. Current therapy to inhibit implant-induced thrombosis is life-long administration of systemic anticoagulants. An alternative to the systemic administration of anticoagulant drugs...
Resource Type:: Masters Thesis
Full Text:: approved: _____________________________________________________________________ Joseph McGuire

Binding of bacterial lipopolysaccharide by the cationic amphiphilic peptide WLBU2 at interfaces

Creator:: Ryder, Matthew P.
Abstract:: Passage of blood through a sorbent device for removal of bacteria and endotoxin by specific binding with immobilized, membrane-active, bactericidal peptides holds promise for treating severe blood infections. Peptide insertion in the target membrane and stable binding is desirable, while membrane disruption and release of degradation products to the circulating...
Resource Type:: Dissertation
Full Text:: Amphiphilic Peptide WLBU2 at Interfaces AN ABSTRACT OF THE DISSERTATION OF Matthew P

Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

Creator:: Auxier, Julie A.
Abstract:: Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate into the hydrophobic inner region of poly(ethylene oxide) (PEO) brush layers; however, the presence of integrated nisin may compromise the protein repulsive character of the PEO layer. In particular, the introduction of fibrinogen to nisin-loaded brush layers has been observed...
Resource Type:: Masters Thesis
Full Text:: : ___________________________________________________________________________ Joseph McGuire Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate

Molecular properties influencing the surface activity of α-lactalbumin, β-lactoglobulin and bovine serum albumin

Creator:: Suttiprasit, Prasert
Resource Type:: Dissertation
Full Text:: : Molecular Properties Influencing the Surface Activity of q-Lactalbumin. p-Lactoglobulin and Bovine Serum

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:: Joshi, Pranav R.
Abstract:: Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...
Resource Type:: Dissertation
Full Text:: : _____________________________________________________________________ Joseph McGuire Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram

Elution of adsorbed proteins at hydrophobic and hydrophilic surfaces by dodecyltrimethylammonium bromide and sodium dodecyls sulfate

Creator:: Vinaraphong, Pravina
Abstract:: Adsorption kinetic data recorded for α-lactalbumin, β-casein, β-lactoglobulin, bovine serum albumin and lysozyme at silianized silica surfaces of low and high hydrophobicity, along with a simple model for adsorption and surfactant-mediated elution of protein, were used to analyze the removal of each protein by sodium dodecylsulfate (SDS) and dodecyltrimethylammonium bromide...
Resource Type:: Masters Thesis
Full Text:: Dodecyls Sulfate Abstract approved: -i—*■*=—i- "t Joseph McGuire Adsorption kinetic data recorded

Sequential and competitive adsorption of BSA and β-lactoglobulin, and their resistance to exchange with [sigma]-lactalbumin and β-casein

Creator:: Nasir, Adil
Resource Type:: Masters Thesis
Full Text:: , followed by contact with protein-free buffer and addition of P-lactoglobulin, most of the adsorbed BSA was

Resistance of adsorbed nisin to exchange with bovine serum albumin, α-lactalbumin, β-lactoglobulin, and β-casein at silanized silica surfaces

Creator:: Muralidhara, Lakamraju
Abstract:: Nisin is an antibacterial peptide, which when adsorbed on a surface can inhibit bacterial adhesion and viability. The ability of noncovalently immobilized nisin to withstand exchange by the milk proteins bovine serum albumin, β-lactoglobulin, α-lactalbumin, and β-casein on surfaces that had been silanized with dichlorodiethylsilane to exhibit high and low...
Resource Type:: Masters Thesis
Full Text:: : Resistance of Adsorbed Nisin to Exchange with Bovine Serum Albumin, a-lactalbumin, P-lactoglobulin, and (3

ScholarsArchive@OSU

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Functionalization of Surfaces with Nisin in a Polyethylene Oxide Brush Layer

Synthesis and anticoagulant function of heparin containing block copolymers on polystyrene microspheres

Binding of bacterial lipopolysaccharide by the cationic amphiphilic peptide WLBU2 at interfaces

Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

Molecular properties influencing the surface activity of α-lactalbumin, β-lactoglobulin and bovine serum albumin

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Elution of adsorbed proteins at hydrophobic and hydrophilic surfaces by dodecyltrimethylammonium bromide and sodium dodecyls sulfate

Sequential and competitive adsorption of BSA and β-lactoglobulin, and their resistance to exchange with [sigma]-lactalbumin and β-casein

Resistance of adsorbed nisin to exchange with bovine serum albumin, α-lactalbumin, β-lactoglobulin, and β-casein at silanized silica surfaces

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search