Index Catalog // ScholarsArchive@OSU

Surface tension kinetics of the wild type and four synthetic, structural stability mutants of bacteriophage T4 lysozyme at the air-water interface

Creator:: Wang, Jun, 1968-
Abstract:: Surface tension kinetics exhibited by selected stability mutants of T4 lysozyme at the air-water interface were monitored with DuNoüy tensiometry. Mutant lysozymes were produced by substitution of isoleucine at position 3 with cysteine, leucine, tryptophan and glycine. Each substitution resulted in an altered structural stability quantified by a change in...
Resource Type:: Masters Thesis
Full Text:: Redacted for Privacy ACKNOWLEDGMENT I would like to thank Dr. Joseph McGuire, my major professor, for

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Creator:: Ryder, Matthew P.
Abstract:: While hydrophobic surfaces coated with the poly[ethylene oxide]-poly[propylene oxide]-poly[ethylene oxide] (PEO-PPO-PEO) surfactant Pluronic® F108 are highly resistant to plasma protein adsorption, the antimicrobial peptide nisin has been observed to adsorb in multilayer quantities at such surfaces, and the PEO chains themselves suggested to inhibit nisin exchange by blood proteins. But...
Resource Type:: Masters Thesis
Full Text:: approved: ________________________________________________________________________ Joseph McGuire

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Creator:: Joshi, Pranav R.
Abstract:: Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram-positive bacteria, was incorporated into novel block copolymer constructs and tested for retained antibacterial activity. Covalent coupling was achieved by chemical modification of the N-terminal isoleucine to introduce a thiol group. Thiolated nisin derivatives were then linked to poly[ethylene...
Resource Type:: Dissertation
Full Text:: : _____________________________________________________________________ Joseph McGuire Nisin, an antibacterial peptide proven to be an effective inhibitor of Gram

Structural effects on enzymatic activity of bacteriophage T4 lysozyme upon adsorption to colloidal silica

Creator:: Xu, Qiurong, 1964-
Resource Type:: Masters Thesis
Full Text:: would like to thank Dr. Joseph McGuire, my major professor, for his valuable guidance, encouragement

Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

Creator:: Auxier, Julie A.
Abstract:: Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate into the hydrophobic inner region of poly(ethylene oxide) (PEO) brush layers; however, the presence of integrated nisin may compromise the protein repulsive character of the PEO layer. In particular, the introduction of fibrinogen to nisin-loaded brush layers has been observed...
Resource Type:: Masters Thesis
Full Text:: : ___________________________________________________________________________ Joseph McGuire Nisin, an amphiphilic, antimicrobial peptide, has been shown to integrate

Interaction of recombinant factor VIII and the nonionic surfactant Tween 80 at interfaces

Creator:: Joshi, Omkar
Abstract:: The role of the nonionic surfactant Tween 80 on the behavior of the therapeutic recombinant protein Factor VIII (rFVIII) was investigated at solid/liquid and air/water interfaces. In order to provide a model system to compare results obtained for the complicated rFVIII-Tween system, a well-characterized globular protein lysozyme was used. The...
Resource Type:: Dissertation
Full Text:: and Joseph McGuiret Department of Chemical Engineering, Oregon State University, Corvallis OR 97331

Adsorption of synthetic stability mutants of bacteriophage T4 lysozyme at silanized silica surfaces

Creator:: Singla, Brijesh
Resource Type:: Masters Thesis
Full Text:: gratitude to Dr. Joseph McGuire, my major professor, for his valuable support and guidance. I would like to

Structural stability effects on adsorption of bacteriophage T4 lysozyme to colloidal silica

Creator:: Tian, Minghua
Abstract:: Circular dichroism (CD) spectra were obtained for bacteriophage T4 lysozyme and three of its mutants in the presence and absence of colloidal silica nanoparticles. Mutant lysozymes were produced by substitution of the isoleucine at position 3 with tryptophan, cysteine and leucine. Each substitution resulted in an altered structural stability, quantified...
Resource Type:: Masters Thesis
Full Text:: my major professor, Dr. Joseph McGuire, for his valuable guidance and full support for my two years

Fibrinogen adsorption at heparinized silica interfaces : history dependence and adsorption time effects

Creator:: Lee, Hyo Jin
Abstract:: Heparin was modified with adipic diliydrazide and covalently linked to surface-activated silica. Contact angle measurements were made to determine changes in surface at various stages of the derivatization. Xray photoelectron spectroscopy was used to analyze the elemental composition of the surface at each step of immobilizing heparin as well and...
Resource Type:: Masters Thesis

Kinetic modeling of the adsorption of structural stability mutants of bacteriophage T4 lysozyme at solid-water interfaces

Creator:: Lee, Woo-Kul
Resource Type:: Dissertation
Full Text:: my major professor, Dr. Joseph McGuire for his support, encourage, and endowing me so many

ScholarsArchive@OSU

Surface tension kinetics of the wild type and four synthetic, structural stability mutants of bacteriophage T4 lysozyme at the air-water interface

Nisin adsorption to PEO-PPO-PEO tri-block copolymer layers and its resistance to elution by fibrinogen

Synthesis and function of bioactive, block copolymer surfactant constructs as relevant to the preparation of anticoagulant and antibacterial medical implant surfaces.

Structural effects on enzymatic activity of bacteriophage T4 lysozyme upon adsorption to colloidal silica

Retention of protein repulsive character and antimicrobial activity of PEO brush layers following nisin entrapment

Interaction of recombinant factor VIII and the nonionic surfactant Tween 80 at interfaces

Adsorption of synthetic stability mutants of bacteriophage T4 lysozyme at silanized silica surfaces

Structural stability effects on adsorption of bacteriophage T4 lysozyme to colloidal silica

Fibrinogen adsorption at heparinized silica interfaces : history dependence and adsorption time effects

Kinetic modeling of the adsorption of structural stability mutants of bacteriophage T4 lysozyme at solid-water interfaces

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search