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Filtering by: Committee Member Zabriskie, Mark T. Remove constraint Committee Member: Zabriskie, Mark T. Advisor Mcphail, Kerry L. Remove constraint Advisor: Mcphail, Kerry L.

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  • Application of modern NMR techniques to structure elucidation of bioactive natural products from tunicates

    Creator:
    Sikorska, Justyna
    Abstract:
    Recent developments in NMR hardware have extended the reach of natural products chemists to structure elucidation of compounds isolated on a nanomolar scale. In parallel with advances in hardware new NMR techniques for structure elucidation have evolved, e.g. quantitative NOEs, residual dipolar couplings (RDCs)and diffusion-ordered spectroscopy (DOSY). The application of...
    Resource Type:
    Dissertation
    Full Text:
    my own projects. I also wish to acknowledge Dr. Philip J. Proteau and Dr. Mark Zabriskie for their

  • Biologically Active Secondary Metabolites from Red Sea Cyanobacteria

    Creator:
    Alhadab, Ali A.
    Abstract:
    This project describes the investigation of marine cyanobacteria collected from the Red Sea with an emphasis on the identification and prioritization of biologically active fractions for future purification and molecular structure elucidation of medicinally relevant secondary metabolites. Five crude extracts of taxonomically unidentified Red Sea cyanobacteria supplied by Egyptian collaborators...
    Resource Type:
    Honors College Thesis
    Full Text:
    Mark Zabriskie ALHADA01 Typewritten Text Christopher Thornburg ACKNOWLEDGMENTS First, I

  • Investigation of unique marine environments for microbial natural products

    Creator:
    Thornburg, Christopher C.
    Abstract:
    Metagenomics has revealed that the marine microbial biosphere is immensely more diverse than originally considered, and is an almost untapped reservoir for the potential discovery of microbial natural products. Despite numerous advances in culturing, biosynthetic engineering and genomic-based screening efforts to uncover much of this diversity in relatively accessible environments,...
    Resource Type:
    Dissertation
    Full Text:
    my very great appreciation to Dr. Mark Zabriskie for your kindness, support and advice throughout

  • Biologically active cyclic depsipeptides from marine cyanobacteria

    Creator:
    Medina, Rebecca A.
    Abstract:
    This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites. A collection of the marine cyanobacterium Lyngbya majuscula from the Radames Islands, Madagascar yielded two new cyclic depsipeptides, radamamides A and B,...
    Resource Type:
    Dissertation
    Full Text:
    . Mark Zabriskie, Dr. Max Deinzer, Dr. Gary DeLander, Dr. Bruce Coblentz and Dr. Doug Markle for their