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Filtering by: Creator Stockberger, Roxy A. Remove constraint Creator: Stockberger, Roxy A. Advisor Proteau, Philip J. Remove constraint Advisor: Proteau, Philip J.

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  • Studies of non-mevalonate isoprenoid biosynthesis : the 1-deoxy-D-xylulose-5-phosphate isomeroreductase (DXR) mediated reaction

    Creator:
    Woo, Youn-Hi
    Abstract:
    This dissertation details the investigation of an alternate pathway to isoprenoids that occurs in plants and microorganisms, the non-mevalonate pathway. This exploration of the pathway focuses on the second step, the conversion of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methylerythritol-4-phosphate (MEP) by the enzyme DXP isomeroreductase (DXR). These studies led to an appreciation...
    Resource Type:
    Dissertation
    Full Text:
    of the stereochemical course of the enzymatic reduction step and to a better understanding of the

  • Studies on isoprenoid biosynthesis in Euglena gracilis

    Creator:
    Kim, Dojung
    Abstract:
    This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
    Resource Type:
    Dissertation
    Full Text:
    isoprenoid biosynthesis in the phytoflagellate Euglena grad/is. Elucidation of a novel isoprerioid pathway