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Filtering by: Creator Carter, Jena Remove constraint Creator: Carter, Jena Advisor Qiu, Weihong Remove constraint Advisor: Qiu, Weihong

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  • Kinesin-14 Motors with Novel Motility Behaviors and Functions

    Creator:
    Feng, Guangxi
    Abstract:
    Cell division, arguably the most important event during the life cycle of the eukaryotic cell, is achieved through a complicated yet beautiful machinery. The mitotic spindle — a microtubule-based bipolar structure—is the cellular machinery responsible for the correct segregation of the genetic material, chromosomes. The protein-based nanomachines termed molecular motors...
    Resource Type:
    Dissertation
    Full Text:
    647-tubulin and 17 µM biotinylated tubulin was first incubated in BRB80 with 0.5 mM GMPCPP (Jena

  • Single-Molecule Characterization of the Stepping Mechanism of the Orphan Kinesin PAKRP2

    Creator:
    Gicking, Allison M.
    Abstract:
    The phragmoplast associated kinesin, PAKRP2, from the model organism Arabidopsis thaliana is categorized as an orphan, or ungrouped, kinesin due to structural divergences from the established 14 kinesin families. An early study on PAKRP2 found that it localized to the phragmoplast mid zone during the late stages of cell division...
    Resource Type:
    Dissertation

  • Mechanisms and Regulation of the Mitotic Kinesin-14 KlpA

    Creator:
    Popchock, Andrew R.
    Abstract:
    Faithful segregation of genetic material during cell division is essential to all life on earth. In eukaryotes, the mitotic spindle – a bipolar array consisting of cytoskeletal filaments called microtubules – is the cellular machinery responsible for this function. The mitotic spindle requires both exquisite spatiotemporal organization and the generation...
    Resource Type:
    Dissertation