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Filtering by: Committee Member Bermudez, Luiz Remove constraint Committee Member: Bermudez, Luiz Advisor Rockey, Daniel Remove constraint Advisor: Rockey, Daniel

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  • Understanding chlamydial biology through genome sequencing and comparative genomics

    Creator:
    Jeffrey, Brendan
    Abstract:
    The human pathogen Chlamydia trachomatis displays different phenotypes between serovars both in vivo and in vitro. The study of chlamydial biology has been hampered by the lack of a tractable genetic system. Here, chlamydial isolates with known phenotypes as well as strains generated though recombination were fully sequenced to address...
    Resource Type:
    Dissertation

  • Analysis of chlamydial and host proteins associated with infection

    Creator:
    Chu, Hencelyn
    Abstract:
    Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their developmental cycle takes place inside non-acidified vacuoles termed inclusions. An inclusion membrane composed primarily of secreted chlamydial synthesized proteins called Incs encloses the inclusion. At this location, Incs have...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Luiz Bermudez, Dr. Mahfuz Sarker, Dr. Karen Guillemin, and Dr. Barbara Taylor who all have an