Index Catalog // ScholarsArchive@OSU

Exploring the Role of Nutrient Sensing Pathways in Blue Light-Induced Lifespan Reduction in Drosophila

Creator:: Shimoda, Kelsey A.
Abstract:: People are increasingly staring at device screens which emit predominantly blue light. Because LED technology is relatively new, we do not know what effects blue light has on our long-term health. Blue light exposure leads to a dramatic decrease in longevity in Drosophila, thus this study aims to explore possible...
Resource Type:: Honors College Thesis

Investigating connections between the circadian system and aging in Drosophila melanogaster

Creator:: Long, Dani M.
Abstract:: Circadian clocks coordinate molecular, cellular, physiological, and behavioral processes with the 24-hour solar day. While clock functions are well understood in young animals, it is not clear how aging or neurodegenerative disease affects the various levels of the circadian system. A common symptom of many neurodegenerative diseases including Alzheimer’s disease...
Resource Type:: Dissertation

The Effects of the Immunity Factor Relish on Aging Phenotypes in Drosophila melanogaster

Creator:: Kumar, Nandita
Abstract:: Aging is a complex biological phenomenon that alters many different physiological processes. Although many age-related phenotypes, such as neurodegeneration, weakening circadian rhythms, and inflammaging, are well-studied, the links between them are not. To elucidate these links we created an inflammation-like state in Drosophila melanogaster by overexpressing Relish (Rel), an NFκB...
Resource Type:: Honors College Thesis

Effects of Oxidative Stress on Circadian Gene Expression during Aging

Creator:: Bonar, Tara
Abstract:: All organisms possess circadian clocks, which generate daily oscillations in clock controlled gene expression that regulate many essential biological functions in synchrony with the 24-hour light/dark cycles. When the genes that control the internal clock are weakened, accelerated aging symptoms are observed. Past research in Drosophila demonstrated that aging flies...
Resource Type:: Honors College Thesis

Exploring Links between Circadian Rhythms and Healthy Aging

Creator:: Mattison, Braden J.
Abstract:: Circadian rhythms are the daily oscillations in multiple organism functions, from clock gene expression to behavior. Lost or irregular rhythms lead to health problems later in life including nervous system disorders, abnormal sleep/activity cycles, diabetes and obesity. However, it is not known whether strengthening the expression of clock genes throughout...
Resource Type:: Honors College Thesis

Exploring functional links between circadian clocks, neurodegeneration, and aging in Drosophila melanogaster

Creator:: Rakshit, Kuntol
Abstract:: Circadian clocks are endogenous molecular mechanisms that coordinate daily rhythms in gene expression, cellular activities, and physiological functions with external day/night cycles. Breakdown of circadian rhythms such as sleep/wake cycles is associated with the onset of several neurological diseases; however, it is not clear whether disruption of rhythms is a...
Resource Type:: Dissertation

Involvement of circadian clock genes in reproduction of Drosophila melanogaster

Creator:: Beaver, Laura M.
Abstract:: Daily (circadian) rhythms exist at molecular, physiological, and behavioral levels and coordinate many life functions. This coordination is believed to contribute to an organism's fitness, however, such contributions have not been convincingly demonstrated in any animal. The most significant measure of fitness is the reproductive output of the individual and...
Resource Type:: Masters Thesis

Oxidative Stress Response Genes: A Circadian Connection?

Creator:: McAllister, Marisa C.
Abstract:: Circadian clocks are internal mechanisms regulating many physiological processes. Research suggests that the circadian clock may regulate repair of cellular damage caused by reactive oxygen species (ROS), but molecular pathways from the clock to ROS repair are not known. The gene cncC, known in mammals as Nrf2, and its repressor...
Resource Type:: Honors College Thesis

You Can’t Beat the Clock: Oxidative Stress and period Mutants in Drosophila melanogaster

Creator:: Davis, Andrew J.
Abstract:: The free-radical theory of aging proposes that intracellular accumulation of oxidative damage caused by reactive oxygen species (ROS) is responsible for the process of senescence. ROS are produced during normal aerobic metabolism and have been shown to cause numerous cellular and sub-cellular defects that lead to termination of the cell...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Exploring the Role of Nutrient Sensing Pathways in Blue Light-Induced Lifespan Reduction in Drosophila

Investigating connections between the circadian system and aging in Drosophila melanogaster

The Effects of the Immunity Factor Relish on Aging Phenotypes in Drosophila melanogaster

Effects of Oxidative Stress on Circadian Gene Expression during Aging

Exploring Links between Circadian Rhythms and Healthy Aging

Exploring functional links between circadian clocks, neurodegeneration, and aging in Drosophila melanogaster

Involvement of circadian clock genes in reproduction of Drosophila melanogaster

Oxidative Stress Response Genes: A Circadian Connection?

You Can’t Beat the Clock: Oxidative Stress and period Mutants in Drosophila melanogaster

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search