The binding of fifteen hydrocarbons to native DNA
has been investigated. The hydrocarbons were chosen to
test a size criterion for hydrocarbon - DNA complexes. It
has been found that hydrocarbons, which are small enough
to intercalate between the base pairs of a distorted Watson -
Crick model of DNA,...
The binding of eleven polycyclic, aromatic hydrocarbons to the acid
form of poly A has been investigated. The hydrocarbons were chosen to
test a size criterion. Model building showed that some hydrocarbons
could intercalate in the helix and be well protected from contact with
the aqueous solvent. Experimentally it was...