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Insight into the regulation of quorum sensing antiactivator genes qteE and qslA in Pseudomonas aeruginosa

Creator:: Lawless, Finn
Abstract:: Ubiquitous pathogen Pseudomonas aeruginosa coordinates population-wide activation of virulence genes through quorum sensing (QS), where individuals transition from solo to social behaviors to benefit the population. QS is complex and mechanisms vary from species to species, but the concept is common to the bacterial world and has implications in various...
Resource Type:: Honors College Thesis

The Social Interactions of Pseudomonas aeruginosa

Creator:: Smith, Parker
Abstract:: Pseudomonas aeruginosa is a ubiquitous environmental microbe, opportunistic pathogen, and a highly social organism. P. aeruginosa utilizes a wide array of cooperative behaviors to adapt to the environmental conditions around it. These behaviors include quorum sensing (QS), a form a cell-to-cell signaling that coordinates the expression of secreted products in...
Resource Type:: Dissertation

Analysis of Mutations Affecting Cooperation in Pseudomonas aeruginosa Populations

Creator:: Robinson, Tanner M.
Abstract:: In a process called quorum sensing (QS), the bacterial pathogen Pseudomonas aeruginosa uses small diffusible signals to coordinate cooperative behaviors via secreted “public goods”. Under QS-dependent growth conditions, social cheaters arise with mutations in lasR, the gene for the primary QS signal receptor. These cheaters do not produce public goods....
Resource Type:: Masters Thesis

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

Creator:: Asfahl, Kyle L.
Abstract:: Cell-cell communication in bacteria is understood to facilitate the coordination of population-wide cooperative behavior in the form of concerted gene expression. The opportunistic pathogen Pseudomonas aeruginosa uses such a communication mechanism to regulate a large group of genes important to virulence strategies in this bacterium. This general mechanism of communication...
Resource Type:: Dissertation

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Creator:: Sexton, David
Abstract:: Cooperative behaviors in bacteria are increasingly appreciated for their relevance to microbial ecology and utility as model systems for social evolution. One example is the secretion of siderophores, a structurally diverse group of compounds that chelate extracellular iron. Siderophore production is considered cooperative because the benefits can be shared with...
Resource Type:: Dissertation

Study on the Evolution and Expression of the Pyoverdine Receptor FpvA inPseudomonas aeruginosa

Creator:: Singh, Amandip
Abstract:: Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium that is capable of causing infections in people who are immune compromised. The bacterium can live in a variety of environments due to the variety of virulence factors it can produce. It is well adapted to living in iron-stringent conditions because it can...
Resource Type:: Honors College Thesis

Studies on the evolution and expression of the Type II ferripyoverdine receptor gene fpvAIIb in Pseudomonas aeruginosa

Creator:: Glover, Rochelle
Abstract:: When iron levels are low, the opportunistic pathogen Pseudomonas aeruginosa secretes the high-affinity iron-binding siderophore pyoverdine. The cognate ferripyoverdine receptor, FpvA, has gained attention as the most divergent gene in the organism’s genome, showing substantial evidence of positive selection. S-type pyocins, bacteriocins with specificity to Pseudomonads, enter cells through FpvA...
Resource Type:: Honors College Thesis

Influence of iron concentration on the expression of the ferripyoverdine receptor gene FpvAIIb of Pseudomonas aeruginosa

Creator:: Glover, Rochelle and Schuster, Martin
Abstract:: Pseudomonas aeruginosa is an environmental bacterium which opportunistically infects humans. Commonly residing in irondepleted environments, P. aeruginosa uses iron-chelating molecules called siderophores to scavenge iron from its environment. The most prevalent siderophore used by P. aeruginosa is known as pyoverdine. After the cell synthesizes and secretes pyoverdine, the molecule binds...
Resource Type:: Poster

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Creator:: Mellbye, Brett L.
Abstract:: Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
Resource Type:: Dissertation

Strain construction to test the significance of antiactivation in Pseudomonas quorum sensing

Creator:: Goff, Shannon Elise
Abstract:: The quorum sensing regulatory pathway has been extensively studied for its impact on the virulence of Pseudomonas aeruginosa, an opportunistic pathogen that causes acute and chronic infections in immunocompromised individuals such as those suffering from the genetic disorder cystic fibrosis. Part of the quorum sensing pathway that has not been...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Insight into the regulation of quorum sensing antiactivator genes qteE and qslA in Pseudomonas aeruginosa

The Social Interactions of Pseudomonas aeruginosa

Analysis of Mutations Affecting Cooperation in Pseudomonas aeruginosa Populations

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

The Fitness Costs and Regulatory Strategies of Cooperative Siderophore Production in Pseudomonas

Study on the Evolution and Expression of the Pyoverdine Receptor FpvA inPseudomonas aeruginosa

Studies on the evolution and expression of the Type II ferripyoverdine receptor gene fpvAIIb in Pseudomonas aeruginosa

Influence of iron concentration on the expression of the ferripyoverdine receptor gene FpvAIIb of Pseudomonas aeruginosa

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Strain construction to test the significance of antiactivation in Pseudomonas quorum sensing

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