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Filtering by: Subject Zebra danio -- Genetics Remove constraint Subject: Zebra danio -- Genetics Contributor advisor sim Tanguay, Robert Remove constraint Contributor advisor sim: Tanguay, Robert

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  • Consequences of miRNA misregulation on embryonic development and aging

    Creator:
    Franzosa, Jill A.
    Abstract:
    microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
    Resource Type:
    Dissertation
    Full Text:
    the many genetic and biochemical processes which contribute to stem cell aging (i.e. telomerase

  • In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

    Creator:
    Usenko, Crystal Y.
    Abstract:
    Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
    Resource Type:
    Masters Thesis
    Full Text:
    Potential of Fullerenes……………… 36 Genetic Reduction of GSH………………………… 37 Lipid Peroxidation Detection