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Filtering by: Alternative title ssim EC 1349 Contributor advisor sim Tanguay, Robert L.

Utilization of the Zebrafish Model for Investigating Nitrated Polycyclic Aromatic Hydrocarbon Developmental Toxicity

Creator:

Chlebowski, Anna C.

Abstract:

Polycyclic aromatic hydrocarbons (PAHs) are among the most widely known and studied environmental contaminants, originating from a range of natural and anthropogenic sources. PAHs are known to occur in the environment as complex mixtures, containing both unsubstituted PAHs, as well as a range of PAH derivatives. Among the less-studied of...

Resource Type:

Dissertation
Classifying Chemical Bioactivity by Coupling High-throughput Phenotypic Anchoring and Transcriptome Profiling in Zebrafish

Creator:

Haggard, Derik

Abstract:

There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...

Resource Type:

Dissertation
Developmental neurobehavioral toxicity of bisphenol A in zebrafish (Danio rerio)

Creator:

Saili, Katerine Schletz

Abstract:

Billions of pounds of bisphenol A (BPA) are produced annually around the globe for the manufacture of numerous consumer products, including polycarbonate food and water containers, the protective resin linings of food cans, thermal printing paper, and dental fillings. BPA exposure during nervous system development has been associated with learning...

Resource Type:

Dissertation

Full Text:

migration limit of 0.6 mg/kg food (Commission Directive 2002/72/EC dated 6 August 2002). Although the