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Filtering by: Subject Microorganisms -- Effect of radiation on Committee Member Alani, Adam

Role of Melanocytic Vitamin D Receptor (VDR) in UVB-induced Melanocyte Homeostasisand Keratinocytic Retinoid–X-Receptor α (RXRα) in UVB Induced Melanomagenesis

Creator:

Chagani, Sharmeen

Abstract:

Cutaneous melanoma remains the deadliest form of skin cancer arising from malignant transformation of pigment-producing melanocytes, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. This DNA damage...

Resource Type:

Dissertation

Full Text:

Chagani for the degree of Doctor of Philosophy in Molecular and Cellular Biology presented on October 4