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Filtering by: Creator Carter, Loren Sheldon Committee Member Blakemore, Paul

Part I: Synthesis and evaluation of synosutine as an inhibitor of serotonin, norepinephrine, and dopamine transporters Part II: Asymmetric approach to the tetracyclic core of neomangicol A

Creator:

Juniku, Rajan B.

Abstract:

Part I: Racemic and asymmetric syntheses of a new substance with prospective antidepressant properties were achieved. In vitro assays with synthetic racemates (±)-25 and (±)-26 suggested that the former is a relatively selective inhibitor of serotonin transporter whereas the latter is a more balanced inhibitor of both serotonin and norepinephrine...

Resource Type:

Dissertation

Full Text:

appreciate all inputs and feedback I received from Professor James White, Professor Rich Carter, Dr. Keith
Evaluation of Bacterial F1FO-ATPase Inhibitors for Synergistic Effects

Creator:

Heppe, Kenan G.

Abstract:

F1FO-ATP synthase targeting antimicrobials apoptolidin 1 (A1), (+)-erythromefloquine, and oligomycin were tested in vitro for synergistic minimum inhibitory concentrations against Staphylococcus aureus. Synergy was strictly defined as inhibition by at most 25% the MIC of each participating drug. Ampicillin, with an MIC of 0.8 ug/mL, served as a negative control....

Resource Type:

Honors College Thesis

Full Text:

]: Antibiotics. Accessed online at scribd.com/doc/7861440/Antibiotics [5]: Sheldon, A. T. Jr. Antibiotic