Greater sage-grouse (Centrocercus urophasianus: hereafter sage-grouse) abundance and distribution in North America has declined over the last century. Many factors have contributed to this decline, including habitat loss and fragmentation from human development with an associated potential for increased predation. While human development has been connected to lower sage-grouse demographic...
Immobilized proteins are integral components of a number of important technologies, including the principal component of many biosensors, as functional coatings in various implants, as catalysts is industrial biosynthesis, and as the building blocks of next-generation nanotechnologies. Despite their ubiquity, relatively little is known about the processes that shape immobilized...
Altogether, this dissertation highlights the value of mass spectrometry-based analysis of intact proteins for solving problems related to understanding disease mechanisms and developing new therapeutics.
Mutations to the antioxidant enzyme Cu, Zn Superoxide Dismutase (SOD1) perturb protein structure in vivo to cause 2-5% of amyotrophic lateral sclerosis (ALS) cases. Metal-deficient...
Auditory defects and disorders are prevalent at all ages and affect 8% of the population in developed nations including newborns and children. Congenital hearing loss is the most common birth defect and it is estimated that 1 in 1000 children are affected by deafness at birth or before the onset...
Education programs at zoos and aquariums provide opportunities for visitors to learn and garner information on animal natural history and, hopefully, conservation messaging. Fee-based programs (programs with an additional fee on top of admission prices), which are commonly employed by zoos and aquariums to foster learning opportunities for visitors, are...
It is good practice to fully understand components of an ecosystem if we hope to preserve its biodiversity. A problem is that we know very little about some organisms and nothing of others. Studies that investigate an organism’s basic biological, ecological and physiological life history variables advance our knowledge of...
Latino students are among the fastest growing demographic groups in the nation, particularly in California, Texas, Florida, and New York. Within California in 2014, over 70,000 students are involved in Agricultural Education programs, and Latino students now account for over 50% of the total enrollment - and the percentage of...
The net mass balance fluctuations of Arctic and Sub-Arctic glaciers, north of 47.5°
North latitude, are described over a 45-year period from 1957 to 2002 using two
parameters derived from a gridded climatology reanalysis. Variability among 185
measured glaciers was represented according to two main components. The first
component represents...